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neurodegenerative diseases/obesitas

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FIELD OF THE INVENTION The present invention relates to a pharmaceutical composition for the treatment and/or prevention of various diseases involving obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases. BACKGROUND OF THE INVENTION Obesity, a
FIELD OF THE INVENTION The present invention relates to a pharmaceutical composition for the treatment and/or prevention of various diseases involving obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases. BACKGROUND OF THE INVENTION Obesity, a

SAB as a biomarker for degenerative diseases and therapeutic sensitivity in cancers

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The Sequence Listing for this application is labeled "SEQ-LIST-07-21-15-ST25.txt", which was created on Jul. 21, 2015, and is 2 KB. The entire content is incorporated herein by reference in its entirety. BACKGROUND OF INVENTION The current technology for diagnosing degenerative diseases focuses on
BACKGROUND OF THE INVENTION Ellagitannins are monomeric, oligomeric, and polymeric polyphenols that are abundant in some fruits, berries and nuts, such as pomegranates, raspberries, strawberries, black raspberries, walnuts and almonds. The fruits and berries are widely consumed fresh and as
BACKGROUND OF THE INVENTION Ellagitannins are monomeric, oligomeric, and polymeric polyphenols that are abundant in some fruits, berries and nuts, such as pomegranates, raspberries, strawberries, black raspberries, walnuts and almonds. The fruits and berries are widely consumed fresh and as
BACKGROUND OF THE INVENTION Ellagitannins are monomeric, oligomeric, and polymeric polyphenols that are abundant in some fruits, berries and nuts, such as pomegranates, raspberries, strawberries, black raspberries, walnuts and almonds. The fruits and berries are widely consumed fresh and as

Use of eupatilin

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TECHNICAL FIELD The present invention relates to novel use of eupatilin. More specifically, the present invention relates to use of eupatilin for the treatment, improvement or prevention of diseases or conditions which are caused by estrogen deficiency, such as bone diseases, menopausal disorders,

Chromenone analogs as sirtuin modulators

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BACKGROUND The Silent Information Regulator (SIR) family of genes represents a highly conserved group of genes present in the genomes of organisms ranging from archaebacteria to eukaryotes. The encoded SIR proteins are involved in diverse processes from regulation of gene silencing to DNA repair.

4-benzimidazol-2-yl-pyridazine-3-one-derivatives, production and use thereof in medicaments

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FIELD OF THE INVENTION The present invention relates generally to pharmaceutical compounds and compositions for the treatment of a number of metabolic disorders that cause diseases of the central nervous system. More specifically, the present invention relates to kinase inhibitor compounds and

1,2,4-thiadiazole derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazole derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic disorders

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazol-2-ium derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazol-2-ium derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazol-2-ium derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic

1,2,4-thiadiazole derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazole derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic disorders

Pyridazinone derivatives, methods for their production and their use as pharmaceuticals

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FIELD OF THE INVENTION The present invention relates generally to the treatment and therapy of certain metabolic diseases such as neurodegenerative diseases such as Alzheimer's disease, Parkinsons' Disease, multiple sclerosis and diabetes. More specifically, the present invention relates to novel
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