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Diffuse macular edema in niacin-induced maculopathy may resolve with dosage decrease.
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OBJECTIVE
To report on a patient with niacin-induced cystic maculopathy that resolved with dosage decrease, not discontinuation, of niacin therapy for dyslipidemia.
METHODS
Retrospective case report. The patient was being followed for vision changes, but his niacin therapy was managed
[Pathophysiological hypothesis regarding the role of nicotinamide in the genesis of niacin-induced macular edema].
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Potentially Reversible Effect of Niacin Therapy on Edema From Retinal Vein Occlusion.
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Macular edema associated with nicotinic acid (niacin)
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Cystoid macular edema from niacin typically is not accompanied by fluorescein leakage on angiography.
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Effect of oral niacin on central retinal vein occlusion.
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OBJECTIVE
Niacin, a treatment for dyslipidemia, is known to induce vasodilation as a secondary effect. Previous instances of patients with chronic central retinal vein occlusion (CRVO) and cystoid macular edema (CME) have been observed to spontaneously improve when placed on systemic niacin for
Decreasing the oxidant stress from paraquat in isolated perfused rat lung using captopril and niacin.
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The abilities of captopril and niacin to protect against the lung toxicity of paraquat (PQ) were studied. The anti-oxidative action of captopril, an angiotensin-converting enzyme inhibitor, appears to be attributable to the sulphahydryl group (SH) in the compound, which gives captopril the ability
Cystoid macular edema induced by low doses of nicotinic Acid.
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Cystoid macular edema (CME) is a condition that involves the macula, causing painless vision loss. In this paper, we report a case of niacin-induced bilateral cystoid macular edema (CME) in a middle-age woman taking low dose of niacin (18 mg of nicotinic acid). Optical coherence tomography (OCT)
Interaction between enfuvirtide, an injectable fusion inhibitor, and niacin in an HIV-infected patient.
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OBJECTIVE
To report a potential drug-drug interaction between enfuvirtide, an injectable HIV fusion inhibitor, and niacin in an HIV-infected man with dilated cardiomyopathy.
METHODS
A 47-year-old HIV-infected man with dilated cardiomyopathy and prolonged QT syndrome with an automatic implantable
Niacin Pretreatment Attenuates Lung Ischemia and Reperfusion-Induced Pulmonary Barrier Function Impairment by Reducing Oxidative Stress and Activating SIRT1 in an Isolated-Perfused Rat Lung Model.
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OBJECTIVE
Alveolar-capillary barrier dysfunction, characterized by alveolar protein leak and lung edema, is a common scenario following cardiopulmonary surgery and thoracic organ transplantation. Reactive oxygen species generated through lung ischemia and reperfusion (I/R) injury during surgery
Drug-induced macular edema.
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Macular edema constitutes a serious pathologic entity of ophthalmology resulting in vision loss with a remarkable impact on the quality of life of patients. It is the final common pathway of various systemic diseases and underlying intraocular conditions, with diabetes mellitus being the most
Safety considerations with niacin therapy.
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Niacin has beneficial effects on plasma lipoproteins and has demonstrated clinical benefits in reducing cardiovascular events and atherosclerosis progression. The side effects of niacin, however, have limited its use in general clinical practice. An understanding of cutaneous flushing based on the
Cystoid macular edema secondary to paclitaxel therapy for ovarian cancer: A case report.
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Paclitaxel is a member of the taxane agents that has demonstrated efficacy in ovarian cancer, both in first- and in second-line therapy. Counted among the side-effects of this drug are neurological disorders. In the present study, a rare case of a non-neuropathic ocular disorder, known as cystoid
Estimation of the niacin requirements for tilapia fed diets containing glucose or dextrin.
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Two 12-wk experiments were conducted to determine the adequate dietary niacin levels for juvenile hybrid tilapia, Oreochromis niloticus x O. aureus, when diets containing either 38% D(+)-glucose or 38% dextrin (type III, from corn) as the carbohydrate source were fed. In Experiment 1, we used 0, 40,
Ocular Effects of Niacin: A Review of the Literature.
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Cystoid macular edema is a condition that involves the macula, caused by an accumulation of extracellular fluid in the macular region with secondary formation of multiple cystic spaces. This condition is provoked by a variety of pathological conditions such as intraocular inflammation, central or
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