otitis externa/protease

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Inflammatory proteases in chronic otitis externa.

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OBJECTIVE Proteases are known to contribute to the pathogenesis of chronic inflammatory skin conditions such as atopic dermatitis and psoriasis. Inhibition of these proteases has shown promise in the treatment of these skin conditions. The purpose of this study was to measure the matrix

Protease activities of Candida spp. isolated from otitis externa: preliminary result.

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Otomycosis is a fungal infection of the ear predominantly caused by Candida and Aspergillus spp. The possible virulence factors of Candida spp. are enzymes, such as proteases, phospholipases, phosphatases and esterase. According to our knowledge, protease production in Candida strains isolated from

Pseudomonas aeruginosa from canine otitis externa exhibit a quorum sensing deficiency.

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Pseudomonas aeruginosa LasB elastase gene (lasB) transcription depends on cell density-dependent quorum-sensing mechanisms of gene activation. Previously, we collected several non-mucoid P. aeruginosa veterinary isolates and showed that the total matrix protease phenotype was similar for isolates

[The pathogenesis of otitis externa].

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In otitis externa the formerly grampositive colonization of the auditory canal changes towards a gramnegative microbial flora. Pseudomonas aeruginosa plays a major role in recurrent infections and in swimmer's ears. Various serotypes of ps. aeruginosa i.e. type 1;6 and 5 could be isolated. In

Assessment and management of chronic otitis externa.

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OBJECTIVE Chronic otitis externa (COE) remains a frustrating problem for both patient and physician. The end stage of disease, medial fibrosing otitis externa, is very challenging to repair. New and old therapies and promising approaches to the treatment of this often recalcitrant problem are

Elastase deficiency phenotype of Pseudomonas aeruginosa canine otitis externa isolates.

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Pseudomonas aeruginosa veterinary isolates were assayed for elastase and total matrix protease activity. The elastase activity of canine ear isolates was much less than that of strain PAO1 and that of all other veterinary isolates (P < 0.0001). The results indicate that canine ear isolates have a

[Phospholipase and proteinase production by Malassezia pachydermatis isolated in dogs with and without otitis].

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BACKGROUND Malassezia pachydermatis is part of the skin microbiota of dogs and cats. M. pachydermatis has been associated with external otitis and seborrhoeic dermatitis, reported more often in dogs than in cats. When the physical, chemical or immunological mechanisms of the skin are altered, M.

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