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[Effects of Panax notoginseng saponins on monophasic action potentials of heart and automaticity and contractility of isolated atria].
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The effects of Panax notoginseng saponins (PNS) on monophasic action potentials (MAP) recorded from the myocardial surface by means of contact electrode were studied in 30 open-chest rabbits. The MAPA was increased and MAPD50, MAPD90 were prolonged with PNS (100, 200 mg.kg-1, iv), while the Vmax
Effect of sugar positions in ginsenosides and their inhibitory potency on Na+/K+-ATPase activity.
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OBJECTIVE
To determine whether ginsenosides with various sugar attachments may act as active components responsible for the cardiac therapeutic effects of ginseng and sanqi (the roots of Panax ginseng and Panax notoginseng) via the same molecular mechanism triggered by cardiac glycosides, such as
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