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phyllanthus acidus/kalium
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Evaluation of antigout activity of Phyllanthus emblica fruit extracts on potassium oxonate-induced gout rat model.
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OBJECTIVE
The present study has been conducted to evaluate antigout activity of aqueous and alcoholic extracts of Phyllanthus emblica fruits following its 28 days repeated oral administration on potassium oxonate-induced gout rat model.
METHODS
The study was conducted on 42 male Sprague-Dawely rats
The relaxant effect of extract of Phyllanthus urinaria in the guinea-pig isolated trachea. Evidence for involvement of ATP-sensitive potassium channels.
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This study analyses the relaxation induced by the hydroalcoholic extract of stems, leaves and roots from Phyllanthus urinaria (Euphorbiaceae) in the guinea-pig trachea (GPT) pre-contracted by carbachol. The hydroalcoholic extract of P. urinaria (0.1-10 mg mL-1) caused a graded relaxation in GPT with
Mechanisms of antihyperuricemic effect of Phyllanthus niruri and its lignan constituents.
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BACKGROUND
Phyllanthus niruri Linn. (Euphorbiaceae) is used as folk medicine in South America to treat excess uric acid. Our initial study showed that the methanol extract of Phyllanthus niruri and its lignans were able to reverse the plasma uric acid of hyperuricemic animals.
OBJECTIVE
The study
Antihyperuricemic lignans from the leaves of Phyllanthus niruri.
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The methanol extract from the leaves of Phyllanthus niruri L. showed oral antihyperuricemic activity in potassium oxonate- and uric acid-induced hyperuricemic rats. Fractionation of the extract by resin chromatography led to the isolation of a less polar fraction which exhibited the highest
Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention.
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Phyllanthus niruri (P.niruri) or stone breaker is a plant commonly used to reduce stone risk, however, clinical studies on this issue are lacking.
To prospectively evaluate the effect of P. niruri on the urinary metabolic parameters of patients with urinary lithiasis.
We studied 56 patients with
Preparation of Lignan-Rich Extract from the Aerial Parts of Phyllanthus niruri Using Nonconventional Methods.
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Phyllanthin and related lignans were found to be responsible, at least in part, for most of the activity of Phyllanthus species. This observation encouraged the authors to develop methods for the preparation of an extract rich in phyllanthin and related lignans from the aerial parts of P.
Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients.
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Phyllanthus niruri is a plant used for years in Brazil to treat urinary calculi. We prospectively evaluated the effect of P. niruri intake on 24 h urinary biochemical parameters in an attempt to assess its in vivo effect in calcium stone forming (CSF) patients. A total of 69 CSF patients (39 males
Antispasmodic effects of an alkaloid extracted from Phyllanthus sellowianus: a comparative study with papaverine.
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Infusions of Phyllanthus sellowianus or P. niruri (Euphorbiaceae) are a popular remedy in Brazil for kidney and bladder stones. This study describes the isolation of an alkaloid from P. sellowianus, denoted ALK-1, and compares its antipasmodic activity with that of papaverine on isolated strips of
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