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primary ovarian insufficiency/tripterygium wilfordii
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A woman with premature ovarian failure induced by Tripterygium wilfordii Hook.f. gives birth to a healthy child.
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OBJECTIVE
To inform clinicians about the reproductive damage of Tripterygium wilfordii Hook.f. (TW) associated with subsequent premature ovarian failure.
METHODS
Case report.
METHODS
Reproductive medicine center in a university-affiliated hospital.
METHODS
A 36-year-old infertile woman presenting
[Establishment of premature ovarian insufficiency kidney deficiency and blood stasis pattern mouse model with Tripterygium wilfordii polyglycoside for Bushen Culuan Decoction therapy].
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To establish a mouse model of premature ovarian insufficiency( POI) with kidney deficiency and blood stasis pattern by Tripterygium wilfordii polyglycoside( TWP) gavage,and to evaluate the ovarian function and fertility of the model,in order to find Bushen Culuan Decoction therapeutic mechanism. 60
Tripterygium glycosides induce premature ovarian failure in rats by promoting p53 phosphorylation and activating the serine/threonine kinase 11-p53-p21 signaling pathway.
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Premature ovarian failure (POF) is a typical pathological disease of the reproductive system in aging females. Infection, inflammation, immune abnormalities, genetic mutation, radiotherapy and chemotherapy can cause POF. Tripterygium glycosides (TGs) are a component extracted from the Chinese herb
Mechanism of resveratrol in improving ovarian function in a rat model of premature ovarian insufficiency.
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OBJECTIVE
To investigate the mechanism of resveratrol treatment in chemically induced premature ovarian insufficiency (POI) in rats.
METHODS
Five-week-old specific pathogen-free healthy Sprague-Dawley female rats (n = 90) were randomly divided into five groups (n = 18): low-dose resveratrol (group
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