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pseudoephedrine/demam
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Sudden death after typhoid and Japanese encephalitis vaccination in a young male taking pseudoephedrine.
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The case of a 21-year-old male taking over-the-counter pseudoephedrine for weight loss who died suddenly during exercise shortly after inoculation with Japanese encephalitis and phenol-inactivated typhoid vaccines is presented. The patient collapsed in mild weather while exercising 75 minutes after
Development of modified-release dosage forms containing loratadine and pseudoephedrine sulfate.
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Pseudoephedrine sulfate (PES) is a short-acting sympathomimetic amine and decongestant. Loratadine (L) is a long-acting antihistamine, H1 blocker. These drugs administered together provide relief from a whole range of rhinitis (hay fever) symptoms. Combination of both drugs is available in the form
An open-label, in-use study assessing the warming sensation accompanying IFF Flavour 316282 and the acceptability and local tolerability of a syrup containing paracetamol and pseudoephedrine for the short-term treatment of symptoms of an upper respiratory tract infection.
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OBJECTIVE
The primary objective was to assess the warming sensation caused by IFF Flavour 316282 in a syrup used for short-term treatment by patients suffering from nasal congestion and mild to moderate body pain, headache, fever or sore throat associated with an upper respiratory tract
The effect of oral drugs on the cytologic picture of nasal mucosa in hay fever.
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The aim of the present study was to assess the influence of H1-antihistamine and sympathomimetic drugs given orally on cytologic smears of the nasal mucosa. Thirty-five patients with hay fever evaluated cytologic smears of the nasal mucosa before and after a 2-week treatment. Fourteen patients
Clinical, double-blind, placebo-controlled study investigating the combination of acetylsalicylic acid and pseudoephedrine for the symptomatic treatment of nasal congestion associated with common cold.
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It was the aim of this clinical study to demonstrate the efficacy of 1000 mg acetylsalicylic acid (ASA, CAS 50-78-2) in combination with 60 mg pseudoephedrine (PSE, CAS 90-82-4), compared with placebo, in the symptomatic treatment of nasal congestion associated with the common cold. A further aim
Factors associated with efficacy of an ibuprofen/pseudoephedrine combination drug in pharmacy customers with common cold symptoms.
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OBJECTIVE
The aim of this study was to explore factors affecting efficacy of treatment of common cold symptoms with an over-the-counter ibuprofen/pseudoephedrine combination product.
METHODS
Data from an anonymous survey among 1770 pharmacy customers purchasing the combination product for treatment
Investigation on temperature-induce conformational change of immobilized β2 adrenergic receptor.
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The β2 adrenergic receptor (β2-AR) is a prototypical family A G protein-coupled receptor (GPCR) and an excellent model system for studying the mechanism of GPCR activation. Purified β2-AR was immobilized on macroporous silica gel to obtain liquid chromatographic stationary phase. The resulting phase
Antihistamines and alpha-adrenergic agents in treatment of otitis media.
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Studies are not available to support the common use of alpha-adrenergic agents and/or antihistamines in the treatment of acute otitis media. A total of 378 patients with acute otitis were entered in a double-blind study comparing treatment results with antibiotics and either placebo,
Cetirizine-associated delusions and depression in an 18-year-old woman.
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BACKGROUND
Cetirizine is a second-generation H1 histamine receptor antagonist that is commonly used for symptomatic relief of hay fever and other allergies and can be combined with pseudoephedrine hydrochloride, a decongestant. The most common adverse effects include headache, nausea,
A novel method to assess antihistamine and decongestant efficacy.
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A method has been developed to equalize as many of the variables as possible in a clinical trial to assess the response to medication in allergic rhinitis. This method was used to study the effectiveness of azatadine maleate and pseudoephedrine sulfate alone and in combination. Azatadine effectively
Bacteriology and treatment of purulent nasopharyngitis: a double blind, placebo-controlled evaluation.
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One hundred forty-two children with purulent nasopharyngitis were randomized to four treatment groups with an antibiotic (cephalexin) alone or combined with a decongestant/antihistamine (pseudoephedrine/triprolidine) or their corresponding placebo equivalents. Follow-up evaluations by parents and
Sinusitis (acute).
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BACKGROUND
Acute sinusitis is defined pathologically, by transient inflammation of the mucosal lining of the paranasal sinuses lasting less than 4 weeks. Clinically, it is characterised by nasal congestion, rhinorrhoea, facial pain, hyposmia, sneezing, and, if more severe, additional malaise and
Sinusitis (acute).
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BACKGROUND
Acute sinusitis is defined pathologically, by transient inflammation of the mucosal lining of the paranasal sinuses lasting less than 4 weeks. Clinically, it is characterised by nasal congestion, rhinorrhoea, facial pain, hyposmia, sneezing, and, if more severe, additional malaise and
[Factors associated with acute febrile reaction in elderly patients receiving intravenous zoledronic acid for osteoporosis].
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OBJECTIVE
To survey the incidence of acute febrile reaction in elderly patients receiving intravenous zoledronic acid for osteoporosis and identify the related factors.
METHODS
Thirty-eight elderly patients with osteoporosis were hospitalized and treated with intravenous infusion of 5 mg zoledronic
Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity.
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The safety profile of paracetamol and simvastatin is sufficiently well known, although no interactions between these two medicinal products have been described in the scientific literature so far. A 66-year-old female patient who experienced myocardial infarction and underwent coronary artery bypass
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