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pseudoephedrine/stroke

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Stroke associated with pseudoephedrine in a child with rhabdomyosarcoma.

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Pseudoephedrine is a nasal vasoconstrictor and is contained in many cough and cold medications. It is generally harmless when used in recommended doses. Hypertensive crisis, psychosis, hemorrhagic stroke, and intracranial hemorrhage have been reported as severe complications. We report a 4-year-old

Cough mixture dependence and stroke: implications for pseudoephedrine regulation.

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Cerebral vasoconstriction and stroke after use of serotonergic drugs.

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Serotonin (5-hydroxytryptamine) is a potent vasoconstrictor amine. The authors report three patients who developed thunderclap headache, reversible cerebral arterial vasoconstriction, and ischemic strokes (i.e., the Call-Fleming syndrome). The only cause for vasoconstriction was recent exposure to

Follow-up study of pseudoephedrine users.

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A follow-up study of over 100,000 persons below age 65 years who filled a total of 243,286 prescriptions for pseudoephedrine indicated that there were no hospitalizations among users that could be attributed to the drug. There were no admissions within 15 days of filling a prescription for

Stroke associated with sympathomimetics contained in over-the-counter cough and cold drugs.

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OBJECTIVE Phenylpropanolamine (PPA) and pseudoephedrine are sympathomimetics contained in over-the-counter cold preparations. A case-control study linked PPA use with hemorrhagic stroke in women. Twenty-two patients with stroke associated with use of these drugs are described. METHODS In a

Pseudoephedrine-induced hemorrhage associated with a cerebral vascular malformation.

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BACKGROUND Sympathomimetic-related intracerebral hemorrhage is well-documented. Most cases are associated with phenylpropanolamine use. METHODS We report a case of intracerebral hemorrhage occurring in a middle-aged man who suffered from chronic sinusitis and had been ingesting pseudoephedrine daily

Decongestant effects on hemodynamics at rest, exercise, and recovery from exercise during--6 degrees of head down tilt.

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OBJECTIVE Ten males were studied to examine the effects of a decongestant, pseudoephedrine hydrochloride, on rest, exercise, and recovery from exercise during -6 degrees of head down tilt (HDT). METHODS Subjects were positioned in the HDT for a total of 6 hr: 2 hr 45 min rest, 30 min exercise, and 2

Adverse events associated with ephedrine-containing products--Texas, December 1993-September 1995.

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During December 1993-September 1995, the Bureau of Food and Drug Safety, Texas Department of Health (TDH), received approximately 500 reports of adverse events in persons who consumed dietary supplement products containing ephedrine and associated alkaloids (pseudoephedrine, norephedrine, and

Water potentiates the pressor effect of ephedra alkaloids.

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BACKGROUND The use of ephedra alkaloids in over-the-counter preparations has been associated with potentially serious cerebrovascular events. Because of its potential association with hemorrhagic strokes, phenylpropanolamine has been largely substituted for by pseudoephedrine, but it is not clear
Ephedrine is a long-studied stimulant available both as a prescription and over-the-counter medication, as well as an ingredient in widely marketed herbal preparations, and is also used as a precursor for the illicit synthesis of methamphetamine. Ephedrine is related to phenylpropanolamine, a

Demographic, pathologic, and toxicological profiles of 127 decedents testing positive for ephedrine alkaloids.

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The relative toxicity of ephedra-containing dietary supplements is disputed. In order to ascertain the magnitude of the problem, we reviewed all autopsies in our Medical Examiner's jurisdiction, from 1994 to 2001, where ephedrine or any its isomers (E+) were detected. Toxicology testing results were

Reversible cerebral vasoconstriction syndrome presenting as an isolated primary intraventricular hemorrhage

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Background: Primary intraventricular hemorrhage is an uncommon cause of stroke and is often associated with longstanding, uncontrolled hypertension. Reversible cerebral vasoconstriction is also an uncommon condition characterized by
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