psoriasis/triglyceride

Retinoids derived from retinol or beta-carotene are inactivated, among other ways, by enzymes belonging to the P450 cytochrome group. Liarozole, an imidazole-containing compound, is known to be a potent inhibitor of the cytochrome P450-mediated metabolism of all-trans retinoic acid. As a result,

Low-dose acitretin is associated with fewer adverse events than high-dose acitretin in the treatment of psoriasis.

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OBJECTIVE In practice, lower dose acitretin therapy (25 mg/d) seems to be better tolerated and associated with fewer abnormalities found after laboratory testing. Here we revisit the original phase 3 trials for acitretin to evaluate the evidence for low-dose therapy producing fewer adverse effects

Lipid profile in patients with psoriasis presenting at Liaquat University Hospital Hyderabad.

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OBJECTIVE To determine the lipid abnormalities in patients with psoriasis and compare it with healthy controls. METHODS Across-sectional controlled study was conducted at the Department of Dermatology Liaquat University Hospital Hyderabad from January 2007 to November 2007. The study included 158

A clinical and epidemiological study of psoriasis and its association with various biochemical parameters in newly diagnosed cases.

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BACKGROUND There has been a lot of recent search on consideration of psoriasis as a systemic disease, with researchers being of the view that dermatological manifestations represent only a part of the spectrum. Although, there have been plenty of studies from the west reporting an association of

Atorvastatin as adjunctive therapy for chronic plaque type psoriasis versus betamethasone valerate alone: A randomized, double-blind, placebo-controlled trial.

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BACKGROUND Psoriasis is a T helper 1 cell-mediated chronic inflammation. Statins have been found to have anti-inflammatory and immunomodulatory effects targeting T helper 1 cells and thus, are being investigated as treatments for psoriasis. OBJECTIVE To investigate the efficacy and safety of

Enteric-coated mycophenolate sodium in psoriasis vulgaris: an open pilot study.

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BACKGROUND Mycophenolate mofetil is a well-known immunosuppressive agent in transplantation medicine. The efficacy of enteric-coated mycophenolate sodium (EC-MPS) was confirmed in other inflammatory skin diseases, including atopic dermatitis and SCLE. OBJECTIVE To investigate the efficacy and the

Factors associated with the length of remission of psoriasis vulgaris.

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BACKGROUND Cardiovascular risk factors are found with significantly high frequency in psoriatic patients. Periods of remission and reactivation of lesions are common in psoriasis. OBJECTIVE Considering the association of chronic inflammation with the atherogenic process, we aimed to search for a

Psoriasis in patients older than 65 years. A comparative study with younger adult psoriatic patients.

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OBJECTIVE To examine the clinical characteristics of psoriasis, prevalence of comorbidities and quality of life in psoriasis patients older than 65 years and to compare them with younger adult psoriatic patients. METHODS Prospective observational study of prevalence. METHODS Patients older than 18

Impaired heart rate recovery indices in psoriasis patients.

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BACKGROUND Psoriasis is a systemic inflammatory disease associated with increased risk of cardiovascular diseases. The heart rate recovery index (HRRI) is an indicator of autonomic nervous system function and is an independent prognostic risk factor for cardiovascular diseases. The aim of this study

Efficacy of food supplement to improve metabolic syndrome parameters in patients affected by moderate to severe psoriasis during anti-TNFα treatment.

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OBJECTIVE Psoriasis is a systemic inflammatory immune-mediated skin disease. Recently a relationship with metabolic syndrome in terms of psoriasis severity and response to therapy was observed. METHODS We performed an open-label randomized controlled study to evaluate the role of a nutraceutical

Psoriasis and phenotype of patients with early inflammatory back pain.

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BACKGROUND Psoriasis is an important clinical feature in spondyloarthritis. However, the influence of psoriasis on the clinical, functional and imaging features of patients with inflammatory back pain (IBP) related to spondyloarthritis is not known. OBJECTIVE To determine the prevalence of psoriasis

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