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pyridoxine/hypoxia
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Effect of pyridoxine, glyoxylic acid and pyridoxylate on oxidative metabolism in vitro and phosphorylated energy-rich compounds studied in rat brains during acute hypoxia and ischaemia.
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Pyridoxine (1-8 mmol/l) did not change significantly the cerebral oxygen nor the hypoxic or ischaemic degradation of phosphocreatine and ATP. Glyoxylic acid (1-8 mmol/l), an inhibitor of the citric acid cycle, depressed the electrically stimulated oxygen uptake of brain slices to a lesser extent
Eosinopenic responses of pyridoxine-deficient rats to epinephrine, adrenocorticotropic hormone and hypoxia.
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NEUROLOGIC RESIDUA OF DELAYED HYPOXIA BENEFITED BY PYRIDOXINE HYDROCHLORIDE SATURATION THERAPY.
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[Effect of pyridoxine on the histochemical behavior of the myocardium in hypoxia].
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[Acid-base variables in the arterial blood of dogs in hypoxia treated with 2-oxo-5-hidroxy-carbonil-pentanoate of pyridoxine (author's transl)].
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Uptake of pyridoxine hydrochloride by the rat jejunal mucosa in vitro.
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The kinetics of mucosal membrane transport of pyridoxine hydrochloride were evaluated in vitro in the rat jejunum. Utilizing everted sacs and a double-label isotope technique, short-term incubation within the period of initial linear tissue uptake indicated: 1) no evidence of saturation of uptake
Effects of pyridoxine supplementation on blood glucocorticoids level, aspartate aminotransferase activity and glucose tolerance pattern under acute hypoxic stress.
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Studies were conducted on male adult rabbits to find out the changes in blood glucocorticoid levels along with the changes in aspartate aminotransferase activity in blood and the role of pyridoxine on the glucose tolerance pattern under hypoxic stress. Hypoxic stress was produced by exposing the
Accumulation of γ-aminobutyric acid in soybean by hypoxia germination and freeze-thawing incubation.
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BACKGROUND
γ-Aminobutyric acid (GABA) can be synthesised by the GABA shunt and polyamine degradation pathway in plants under hypoxia stress and lower temperature. The hypoxia germination freeze-thawing incubation was used as a new technique for accumulating more GABA in soybean.
RESULTS
Results
[The effect of pyridoxine on the cerebral hemodynamics in vestibular disorders].
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By means of hydrogen clearance on conscious rabbits with implanted platinum electrodes it was established that pyridoxine (1 and 10 mg/kg) used against the background of sea sickness decreased the dilatational reaction of the cerebral vessels occurring during the stimulation of the vestibular
Gastrointestinal absorption of vitamin B-6 in the chicken (Gallus domesticus).
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The absorption of vitamin B-6 from the gastrointestinal tract of the chicken (Gallus domesticus) was studied by using ligated segments in vivo, everted jejunal sacs in vitro, and in intact birds. [3H]Pyridoxine hydrochloride ([3H]PN . HCl) was absorbed from all sections of the small intestine, from
Neonatal seizures: diagnosis and management.
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The recognition of epileptic seizures in newborns is challenging as neonates exhibit a variety of paroxysmal motor phenomena, some epileptic but others not. The distinction, frequently requiring video-EEG monitoring, is crucial for management. Causes are often multi-factorial, specific to
Effects of piridoxilate, a glyoxylic acid derivative, on the energy metabolism of the heart.
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Piridoxilate is a conjugation product of pyridoxine and glyoxylic acid, which may be a physiological regulator of cell respiration. Effects of this substance on the oxidation-reduction state of the pyridine nucleotides in the heart were studied using the canine heart-lung preparation supported by a
[Intermittent convulsions for 1.5 years and psychomotor retardation in a girl].
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The study reports a girl with pyridoxine-dependent epilepsy. The girl was admitted at the age of 2 years because of intermittent convulsions for 1.5 years and psychomotor retardation. She had a history of "hypoxia" in the neonatal period. At the age of 5 months recurrent epileptic seizures occurred.
Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
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The deazaflavin cofactor F420 enhances the persistence of mycobacteria during hypoxia, oxidative stress, and antibiotic treatment. However, the identities and functions of the mycobacterial enzymes that utilize F420 under these conditions have yet to be resolved. In this work, we used sequence
[Problems of the therapy of neonatal convulsions].
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The newborn with seizures should be treated urgently, because of the high risk of consequent brain damage. In addition to general management in order to correct metabolic and functional unbalancement, associated with the fits, specific causes of neonatal seizures (hypoglicemia, hypocalcemia,
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