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quinine/stroke

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Was It Malarious Fever or Sun-Stroke Cured by Quinine?: Naturam Morborum Remedia Ostendunt.

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Heat Apoplexy Treated with Quinine; Recovery.

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Newly designed gustatory test based on the number of chewing strokes required for recognition of the taste.

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OBJECTIVE The purpose of this study was to examine the usefulness of a new gustatory test based on the progress of mastication by counting the number of chewing strokes required for recognizing tastes. METHODS Thirty-nine subjects (20 males and 19 females, 25.3±6.4 years old) without missing teeth

Taste perception abnormalities after acute stroke in postmenopausal women.

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The study aims to elucidate the characteristics of post-stroke taste dysfunction in postmenopausal women. Taste function in 120 consecutive postmenopausal women with acute (<7 days) stroke was compared with that of age-matched control subjects (n=109). The agents used were: sodium chloride for

Modulation of Acid-sensing Ion Channel 1a by Intracellular pH and Its Role in Ischemic Stroke.

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An important contributor to brain ischemia is known to be extracellular acidosis, which activates acid-sensing ion channels (ASICs), a family of proton-gated sodium channels. Lines of evidence suggest that targeting ASICs may lead to novel therapeutic strategies for stroke. Investigations of the

Age related decreases in neural sensitivity to NaCl in SHR-SP.

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To determine whether neurophysiological taste responses of young and old rats are different, recordings were made from the whole chorda tympani nerve which innervates taste buds on the anterior tongue. SHR-SP (Stroke-Prone Spontaneously Hypertensive Rats) in two age groups were studied. Chemical

Tactile interaction with taste localization: influence of gustatory quality and intensity.

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Taste is always accompanied by tactile stimulation, but little is known about how touch interacts with taste. One exception is evidence that taste can be "referred" to nearby tactile stimulation. It was recently found (Lim J, and Green BG. 2007. The psychophysical relationship between bitter taste

Taste perception and diet in people of Chinese ancestry.

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OBJECTIVE Taste perception plays a key role in consumer acceptance and food choice, which has an important impact on human health. Our aim was to examine the relationship between taste intensities and preferences of sweet (sucrose), salty (sodium chloride and potassium chloride), sour (citric acid),

Increase in Cx45 gap junction channels in cerebral smooth muscle cells from SHR.

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We recently reported the novel finding of expression and function of connexin45 (Cx45) in cerebrovascular smooth muscle cells. We examined the hypothesis that Cx45 is altered in hypertension. Immunoblots for Cx45 showed a significant increase in Cx45 in cerebral arteries from adult spontaneously
While there is evidence that gap junctions play important roles in the determination of cell injuries, there is not much known about mechanisms by which gap junctional communication may exert these functions. Using a global model of transient ischaemia in rats, we found that pretreatment with the

[Drug treatments of atrial fibrillation].

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Atrial fibrillation is a daily cardiological problem which poses three types of questions, which, though old, are only partially mastered: anticoagulation, reduction and prevention of recurrence. It is a potent source of embolism. The risk is the greatest in patients with rheumatic valvular disease

Artesunate-erythropoietin combination for murine cerebral malaria treatment.

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Cerebral malaria is the most severe and rapidly fatal complication of Plasmodium falciparum infection. Despite appropriate anti-malarial treatment using quinine or artemisinin derivatives, 10-20% of mortality still occurs during the acute phase. To improve cerebral malaria outcome, adjunctive

Preventive and Protective Roles of Dietary Nrf2 Activators Against Central Nervous System Diseases.

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Central nervous system diseases are major health issues and are often associated with disability or death. Most central nervous system disorders are characterized by high levels of oxidative stress. Nuclear factor erythroid 2 related factor (Nrf2) is known for its ability to regulate the expression
Oxidative damage plays a critical role in many diseases of the central nervous system. This study was conducted to determine the molecular mechanisms involved in the putative anti-oxidative effects of sevoflurane against experimental stroke. Focal cerebral ischemia was performed via 1h of middle
Background: Cerebral ischemia (CI) can lead to ischemic stroke. The most effective therapy for cerebral ischemic stroke is the early restoration of blood reperfusion. However, reperfusion after CI can result in cerebral ischemia
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