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respiratory insufficiency/mual

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Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection

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Ta1 is a naturally occurring peptide that has been evaluated for its immunomodulatory activities and related therapeutic potential in several conditions and diseases, including infectious disease and cancer. ZADAXIN® brand Ta1 is a synthetic version currently approved for use in 37 countries; in

Suloexide in the Treatment of Early Stages of COVID-19

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Objective: To use sulodexide in patients that have early onset of COVID-19 symptoms to mitigate the progression of the disease process that can allow them to recover at home, and limit the need for hospital care and the more severe manifestation which includes fulminant respiratory failure, acute

Topical Bupivacaine Effect On The Response To Awake Extubation During Emergence From General Anesthesia

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The process of manipulation of the airway during laryngoscopy, endotracheal intubation, and extubation is usually associated with exaggerated hemodynamic response including tachycardia, hypertension as well as increase intraocular and intracranial pressure[1,2]. The exact mechanism to these

Role of Co-trimoxazole in Severe COVID-19 Patients

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Coronavirus disease (COVID-19) caused by SARS-COV2, represents a highly transmissible and potentially fatal disease that is of great global public health concern at this moment. The pandemic situation in Bangladesh is also evolving rapidly with positive cases and deaths increasing each day.

Superficial Cervical Plexus Block for Orthognathic Surgery

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Postoperative pain management is very important in patients underwent orthognathic surgery. Effective pain control provides early mobilization, shorter hospital stay and it increases the satisfaction of the patients. Opioid agents may provide effective pain management, however opioid agents have

Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris

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Results of the IMPRESSION trial published in 2015 proved that morphine use in patients with acute coronary syndromes (ACS) is associated with undesirable impact on pharmacokinetics (PK) and pharmacodynamics (PD) of ticagrelor. Despite that, morphine is still a standard analgesic treatment in ACS

Cerebral Compliance Impairment in COVID-19

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The gravity of the disease caused by the new coronavirus 2019 (COVID-19) is predominantly harbored in severe acute respiratory syndrome (SARS), often requiring ventilatory support. However, in some cases it has been observed that the involvement of this entity is not restrict to the respiratory

Fentanyl Versus Midazolam As Additives To Bupivacaine In Ultrasound Guided Transversus Abdominis Plane Block

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Informed written consent will be obtained from study participants or their legally authorized representative. This is a randomized controlled double blinded study; patients will be enrolled in the study and will be randomized and equally divided into three groups: Group A: (TAP block with 20 ml of

Comparison of Ultrasound Guided Genicular Nerve Block and Periarticular Infiltration in Knee Arthroplasty

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Total knee arthroplasty (TKA), one of the most commonly performed operations in orthopaedic department, has been a successful intervention for patients with end-stage knee arthritis. Rehabilitation after total knee arthroplasty (TKA) routinely starts immediately after surgery on the postoperative

Single Shot Lumbar Erector Spinae Plane (ESP) Block in Total Hip Replacement (THR)

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After a pilot study regarding opioid use for patient after THR, the sample size for either treatment or control arm is calculated to be 35 patients per group to achieve adequate power to detect such a difference. Sealed opaque envelopes with allocation inside is prepared forehand and is subsequently

Ivermectin and Nitazoxanide Combination Therapy for COVID-19

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Selected Drugs Ivermectin has anti-parasitic effect along with anti-viral activity against a broad range of viruses in vitro. Ivermectin was identified as an inhibitor of interaction between the human immunodeficiency virus-1 (HIV-1) integrase protein (IN) and the importin (IMP) α/β1 heterodimer

Hydroxychloroquine and Nitazoxanide Combination Therapy for COVID-19

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Selected Drugs Hydroxychloroquine (an analog of chloroquine) has been demonstrated to have an anti-SARS-CoV activity in vitro. Hydroxychloroquine clinical safety profile is better than that of chloroquine (during long-term use) and allows higher daily dose and has fewer concerns about drug-drug

Systemic Absorption of Lidocaine After Hematoma Block

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When a subject with an eligible distal forearm fracture is identified, the subject will be approached for enrollment and consent. Fracture hematoma size will then be estimated using bedside ultrasound operated by trained pediatric emergency faculty or fellows. Ultrasound measurement of the

Lidocaine Combined With Low Opioid Anesthesia and Analgesia in Patients With Primary Liver Cancer

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200 patients with primary liver cancer who meet the standard are included. According to the random number, the patients are divided into lidocaine group and conventional analgesia group. Changes in liver and kidney function, blood routine, blood coagulation function and tumor marker
Low dose perioperative ketamine infusion and it's effect on postoperative pain score, sedation score and narcotic consumption in patients undergoing spine surgery: A prospective randomized double blind control trial. INTRODUCTION: Recent advances in pain management advoctes the use of multimodal
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