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salpingitis/progesterone
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The effect of a single oral dose of azithromycin on chlamydial salpingitis in mice.
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Progesterone-treated C3H mice were inoculated under the ovarian bursa with a human Chlamydia trachomatis strain, serovar E, and treated variously from one week before inoculation to two weeks afterwards with a single oral dose of azithromycin. At autopsy, all 27 control mice, not given azithromycin,
Salpingitis in mice induced by human strains of Chlamydia trachomatis.
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Human strains of Chlamydia trachomatis were inoculated unilaterally into the genital tracts of female TO, CBA, CBA/nu and C3H mice via the intrauterine route or under the ovarian bursa. Inflammatory changes were not seen in the oviducts or uterus of mice given two laboratory-adapted LGV serovars (L1
Will progesterone save the IUD?
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In 1971 we began studying pelvic inflammatory disease (PID) in IUD users by examining fallopian tube specimens obtained after elective female sterilization. We studied four groups: 175 nonhormonal-IUD users, 22 Progestasert users, 1,500 non-IUD users and 100 non-IUD users who had had IUDs in the
Correlation of infertility with altered tubal morphology and function in mice with salpingitis induced by a human genital-tract isolate of Chlamydia trachomatis.
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Progesterone-treated C3H mice were inoculated into the uterus or ovarian bursa with a human genital tract isolate of C. trachomatis (serovar E), or with control medium alone. The mice were then observed at various times up to 260 days after inoculation. Before being killed the mice were given
Oral contraceptives do not alter the course of experimentally induced chlamydial salpingitis in monkeys.
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OBJECTIVE
The effects of oral contraceptive use on chlamydial infections and ensuing PID are not well understood. In this study, the effects of oral contraceptives on the clinical course of acute chlamydial salpingitis were investigated.
METHODS
Monkeys (n = 4) in which salpingeal auto-transplants
Reappearance of the intrauterine device: a 'user-friendly' contraceptive.
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Women in the United States, and their physicians, are "rediscovering" intrauterine devices (IUDs). Two IUDs, the 10-year Copper T 380A (Paragard) and 1-year progesterone-releasing T (Progestasert) are currently marketed in this country. In contrast to previous perceptions, recent studies have
Nodular histiocytic hyperplasia of the endometrium.
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A case of nodular histiocytic hyperplasia of the endometrium is described. A 45-year-old Japanese woman was found to have an enlarged uterus during her annual checkup. Hysterectomy and bilateral salpingo-oophorectomy specimens revealed uterine leiomyomas, adenomyosis, and acute salpingitis. A 5-mm,
[Follicular development patterns in infertile women with biphasic basal body temperature].
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Seventy-one cases of infertile women with both normal menstrual cycle and biphasic BBT were studied with ultrasonography, laparoscopy, hormonal assay and endometrial histology. Signs for follicular development and ovulation were divided into four types: (1) normal ovulation in 12 cases; (2)
Estrone and dehydroepiandrosterone sulfatase activities in normal and pathological human endometrium biopsies.
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The properties of estrone (E1) and dehydroepiandrosterone (DHEA) sulfatase activities are reported. Endometrial biopsy specimens were obtained using a Novak curette. Cycle stage was assessed from histological dating of endometrium, plasma estradiol and progesterone levels, and patient history. Both
The effect of a single oral dose of azithromycin on chlamydial infertility and oviduct ultrastructure in mice.
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Azithromycin has been recommended for the treatment of human chlamydial genital tract infections because of the sustained, chlamydicidal levels of the antibiotic which can be achieved after a single dose. The effect of single dose azithromycin on the prevention or reversal of chlamydial-induced
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