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7 hasil
Identification and characterisation of serotonin signalling in the potato cyst nematode Globodera pallida reveals new targets for crop protection
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Plant parasitic nematodes are microscopic pathogens that invade plant roots and cause extensive damage to crops. We have used a chemical biology approach to define mechanisms underpinning their parasitic behaviour: We discovered that reserpine, a plant alkaloid that inhibits the vesicular monoamine
Bioassay-guided isolation of serotonin from fruits of Solanum tuberosum L.
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An ethanol extract of the fruits of Solanum tuberosum was partitioned between water and petroleum ether. The aqueous fraction had contractive effect on the isolated guinea-pig ileum. Chromatography of this fraction on Sephadex LH-20 and silica gel was monitored by the guinea-pig ileum test and
Laser desorption ionization mass spectrometry in the study of natural and synthetic melanins. II--Serotonin melanins.
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Various biosynthetic melanins obtained by enzymic oxidation of serotonin with polyphenol oxidase from Psalliota campestris mushroom or potato, and with tyrosinase from Sepia officinalis or from Sigma were studied by means of laser desorption ionization mass spectrometry. Various oligomeric clusters
Brain serotonin, carbohydrate-craving, obesity and depression.
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Serotonin-releasing brain neurons are unique in that the amount of neurotransmitter they release is normally controlled by food intake: Carbohydrate consumption--acting via insulin secretion and the "plasma tryptophan ratio"--increases serotonin release; protein intake lacks this effect. This
Melatonin, serotonin, and tryptamine in some egyptian food and medicinal plants.
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The mammalian pineal hormone melatonin (N-acetyl-5-methoxytryptamine), an aminoindole produced by the metabolism of serotonin (5-hydroxytryptamine), has been shown to be a potent scavenger for the highly toxic hydroxyl radical. Three substances that are very important in animal physiology (e.g., in
Characterization of Cbl-Nck and Nck-Pak1 interactions in myeloid FcgammaRII signaling.
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Fc receptors modulate inflammatory processes, including phagocytosis, serotonin and histamine release, superoxide production, and secretion of cytokines. Aggregation of FcgammaRIIa, the low-affinity receptor for monomeric IgG, activates nonreceptor protein tyrosine kinases such as Lyn, Hck, and Syk,
Improved method for the determination of biogenic amines and polyamines in vegetable products by ion-pair high-performance liquid chromatography.
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Here, we report on the optimisation and validation of a liquid chromatographic method for the determination of 12 biologically active amines from vegetal food products in a single 40-min run. The suitability of the method was checked in five vegetal products of distinct matrix: spinach (leaves),
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