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sesamum/antikanker
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Carboxymethylcellulose hybrid nanodispersions for edible coatings with potential anti-cancer properties.
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Curcumin loaded lipid-polymer hybrid nanoparticles dispersions were fabricated from carboxymethylcellulose, stearic acid, polyethylene glycol and sesame oil using emulsion solvent evaporation method for their possible application as edible coatings for fresh vegetables and fruits. They were
[Antitumor effect of alcohol extract from Sesamum indicum flower on S180 and H22 experimental tumor].
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OBJECTIVE
To investigate the antineoplasm effect of extract from Sesamum indicum L. flower.
METHODS
Observing the effects of alcohol extract from Sesamum indicum flower on tumor growth in sarcoma 180 (S180) and Heps 22 (H22) tumorigenic mouse, and on weight of immune organs.
RESULTS
6, 3, 1.5 g/kg
Eco-friendly green synthesis of silver nanoparticles from the sesame oil cake and its potential anticancer and antimicrobial activities.
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In recent years, much attention is focused on silver nanoparticles for biomedical applications and then synthesis using plant procedure has drawn a great focus. In the current study silver nanoparticles were synthesized using the oil cake of Sesamumindicum, which has been used traditionally for
Systemic treatment with n-6 polyunsaturated fatty acids attenuates EL4 thymoma growth and metastasis through enhancing specific and non-specific anti-tumor cytolytic activities and production of TH1 cytokines.
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Recently, there has been a great interest in the effects of different types of n-6 polyunsaturated acids (n-6 PUFAs) upon the immune system and cancer development. However, the effects of n-6 PUFAs are still controversial and as yet undefined. The present study aimed to investigate the anti-tumor
[Antitumor effect of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha, alpha-trehalose (SS 554) in mice].
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The antitumor effect of a synthetic cord factor (6, 6'-Di-O-decanoyl-alpha, alpha-trehalose) (SS 554) on the growth of Meth-A fibrosarcoma in BALB/c mice was examined. With regard to administration routes, only intratumoral (i.t.) injection showed a curative effect; subcutaneous (s.c.), per oral
Antitumor effect of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha,alpha-trehalose (SS554), in mice.
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The antitumor effect on Meth-A fibrosarcoma in BALB/c mice of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha,alpha-trehalose (designated as SS554), was examined. Only intratumoral injection had a curative effect; subcutaneous, per oral, or intravenous routes had no such effect. The co-presence of
Preparation, characterization and in-vivo evaluation of microemulsions containing tamoxifen citrate anti-cancer drug.
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The aim of this study was to prepare and characterize a new nanocarrier for oral delivery of tamoxifen citrate (TMC) as a lipophilic oral administrated drug. This drug has low oral bioavailability due to its low aqueous solubility. To enhance the solubility of this drug, the microemulsion system was
Anticarcinogenic and hepatotoxic interactions between retinyl acetate and butylated hydroxytoluene in rats.
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The natural retinoid, retinyl acetate (RA), and the phenolic antioxidant, butylated hydroxytoluene (BHT), are both effective inhibitors of mammary carcinogenesis in rats. The present study was designed to determine if an increased inhibition of mammary carcinogenesis is obtained when RA and BHT are
Sesamol exhibits antimutagenic activity against oxygen species mediated mutagenicity.
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The effects of sesamol, a phenolic compound responsible for the high resistance of sesame oil to oxidative deterioration as compared with other vegetable oils, have been investigated after mutagen treatment in various strains of Salmonella typhimurium. Sesamol was shown to exhibit strong
Anti-Inflammatory and Anticancer Properties of Bioactive Compounds from Sesamum indicum L.-A Review.
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The use of foodstuff as natural medicines has already been established through studies demonstrating the pharmacological activities that they exhibit. Knowing the nutritional and pharmacological significance of foods enables the understanding of their role against several diseases. Among the foods
Antineoplastic Effects of Honokiol on Melanoma.
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Honokiol, a plant lignan has been shown to have antineoplastic effects against nonmelanoma skin cancer developments in mice. In this study, antineoplastic effects of honokiol were investigated in malignant melanoma models. In vitro effects of honokiol treatment on SKMEL-2 and UACC-62 melanoma cells
Evaluation of anti-cancer and anti-oxidative potential of Syzygium Cumini against benzo[a]pyrene (BaP) induced gastric carcinogenesis in mice.
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Syzygium cummini extract (SCE) was used in the present study to explore anti-tumor promoting activity in a stomach carcinogenesis model in mice. For this purpose, Swiss albino mice were administered with 1 mg of benzo-a-pyrene (BaP) in 100?l sesame oil by oral gavage twice a week for 4 consecutive
Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action.
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Sesamol is a natural phenolic compound and a major lignan isolated from sesame seeds (Sesamum indicum) and sesame oil. The therapeutic potential of sesamol was investigated intensively, and there is compelling evidence that sesamol acts as a metabolic regulator that possesses antioxidant,
A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum).
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Sesamin is the major active ingredient is Sesamum indicum seeds. Several studies revealed that sesamin possesses potent anti-cancer properties. The anti-cancer effects of sesamin have been mainly attributed to its anti-proliferative, pro-apoptotic, anti-inflammatory, anti-metastatic, anti- and
Anticarcinogenic effect of N6,O2'-dibutyryl cyclic adenosine 3':5'-monophosphate on 7,12-dimethylbenz(a)anthracene mammary tumor induction in the rat and its relationship to cyclic adenosine 3':5'-monophosphate metabolism and protein kinase.
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A single intubation of 7,12-dimethylbenz(a)anthracene (DMBA) (20 mg in 1 ml sesame oil) to female Sprague-Dawley rats at 50 days of age produces primary mammary carcinomas in 80% of rats at 100 to 150 days of age. Administration of N6,O2'-dibutyryl cyclic adenosine 3':5'-monophosphate (DBcAMP) p.o.
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