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Development of sarcomas in Marshalbino mice following injection of desoxycorticosterone acetate in sesame oil.
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Development of sarcomas in Marsh albino mice following injection of desoxycorticosterone acetate in sesame oil. II.
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Characterization of chemically induced ovarian carcinomas in an ethanol-preferring rat model: influence of long-term melatonin treatment.
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Ovarian cancer is the fourth most common cause of cancer deaths among women, and chronic alcoholism may exert co-carcinogenic effects. Because melatonin (mel) has oncostatic properties, we aimed to investigate and characterize the chemical induction of ovarian tumors in a model of ethanol-preferring
Oncogenicity of K-region epoxides of benzo(A)pyrene and 7,12-dimethylbenz(A)anthracene.
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Female Sprague-Dawley rats were given a subcutaneous injection of the parent hydrocarbon or its K-region epoxide in 0.1 ml sesame oil on alternate days to a total of 30 doses and observed for sarcoma at the site of injection for 275 days. The parent compounds, benzo(a)pyrene (0.2 mumole/dose) and
Identification and characterization of a specific autoantiphosphatidylinositol immune response during the time course of benzo(a)pyrene-induced malignant tumors in female Sprague-Dawley rats.
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High levels of anti-phosphatidylinositol (PtdIns) autoantibodies (autoAb) have been previously described in sera of cancer patients and in plasma of dimethylbenzanthracene-treated female Sprague-Dawley rats. The presence of anti-PtdIns autoAb was tested in a model of highly malignant sarcomas
The effect of hypophysectomy on 9,10-dimethyl-1,2-benzanthracene-induced carcinogenesis [abstract].
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In view of the findings of Moon, Simpson, and Evans (Science, 116:331,1952) that the hypophysectomized rat was refractory to the carcinogenic effect of methyl-cholanthrene, similar experiments have been conducted but using the more powerful carcinogen 9,10-dimethyl-1,2-benzanthracene. The results of
[Antitumor effect of alcohol extract from Sesamum indicum flower on S180 and H22 experimental tumor].
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OBJECTIVE
To investigate the antineoplasm effect of extract from Sesamum indicum L. flower.
METHODS
Observing the effects of alcohol extract from Sesamum indicum flower on tumor growth in sarcoma 180 (S180) and Heps 22 (H22) tumorigenic mouse, and on weight of immune organs.
RESULTS
6, 3, 1.5 g/kg
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