The control group will receive usual perioperative care including patient education on diagnosis, treatment and prognosis of skin cancer, encouragement of food and fluid intake prior to and during the surgery as needed, and acetaminophen per patient request.

The intervention group, in addition to usual care, will receive Acetaminophen 1000mg and commercially available carbohydrate drink (two pouches of Gatorade Prime Sports Fuel drink containing 50gm carbohydrate in approximately 250ml fluid total) at the beginning of the surgery.

Control

The intervention group, in addition to usual care, will receive Acetaminophen 1000mg and commercially available carbohydrate drink (two pouches of Gatorade Prime Sports Fuel drink containing 50gm carbohydrate in approximately 250ml fluid total) at the beginning of the surgery.
Acetaminophen: Acetaminophen 1000mg

Intervention

Total

Sex: Female, Male

Race (NIH/OMB)

Region of Enrollment

Rated on a pain scale of 0-100. Higher score means worse outcome; lower score means better outcome.

Pain scale

Maximum Pain Score

Rated on a thirst scale of 0-100. Higher score means worse outcome; lower score means better outcome.

Thirst

Rated on a hunger scale of 0-100. Higher score means worse outcome; lower score means better outcome.

Hunger

Rated on n anxiety scale of 0-100. Higher score means worse outcome; lower score means better outcome.

Anxiety

Rated on a fatigue scale of 0-100. Higher score means worse outcome; lower score means better outcome.

Fatigue

Number of participants using over the counter and prescribed non-opioid and opioid pain medications

Number of Participants Using Post-operative Analgesic

Rated on a maximum post-op pain scale of 0-100. Higher score means worse outcome; lower score means better outcome.

Maximum Post-op Pain Score

Overall Study

Bichchau Nguyen, Principal Investigato

Non-melanoma Skin Cancer

Acetaminophen

Tufts Dermatology

Preoperative Acetaminophen and Carbohydrate Loading

Impact of Preoperative Acetaminophen and Carbohydrate Loading to on Pain and Functional Status in Patients Undergoing Mohs Micrographic Surgery for Non-melanoma Skin Cancers

Tufts Medical Center

Patients will undergo an MRI for assessment of the fat content of the liver. Then during surgery, their livers will be illuminated (for a few seconds) by Raman spectroscope (the device in question) to see if MRI findings correlate well with Raman spectroscopy findings.

Steatosis

Liver will be illuminated by the Raman spectroscope optic probe in order to assess fat content

Raman spectroscopy of the liver

Clinical Validation of a Raman Spectroscope to Determine Hepatic Fat Content

Clinical Validation of High Throughput Raman Fiber Optic Probe to Determine Hepatic Fat Content

Sertac Cimen

Medical Fellow

Treatment with 4.8 grams PectaSol-C Modified Citrus Pectin three times a day, away from meals for six months.

Prostatic Neoplasms

Oral administration of PectaSol-C MCP (4.8 grams in six capsules three times a day away from food).

PectaSol-C Modified Citrus Pectin (MCP)

Genitourinary Oncology Service, Institute of Oncology, Meir Medical Center, Tshernichovsky 59,

Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA

Phase III, Single-Center, Open Label, Trial Evaluating the Safety and Efficacy of PectaSol-C Modified Citrus Pectin on PSA Kinetics in Prostate Cancer in the Setting of Serial Increases in PSA

PSA doubling time increase will be used to show effectiveness of the Modified Citrus pectin (MCP).

Patient tolerability of MCP will be assessed by comparing the results of weekly self-assessment diaries with baseline assessments.

At baseline (0 month), and end of study (6 month): Blood draw for serum levels of galectin-3, C-reactive protein, and lipid panel.

EcoNugenics

Dietary Supplement: PectaSol-C Modified Citrus Pectin (MCP) Oral administration of PectaSol-C MCP (4.8 grams in six capsules three times a day away from food).

Subjects were educated about a low fat diet plus exercise and then followed for weight loss. They were also asked to monitor their physical activity by wearing a pedometer and recording the total steps walked every day.

Subjects were educated about a low carbohydrate diet plus exercise and then followed for weight loss. They were also asked to monitor their physical activity by wearing a pedometer and recording the total steps walked every day.

Breast Cancer

Weight Loss

Low fat diet plus exercise - Subjects were educated about a low fat diet plus exercise and then followed for weight loss. They were also asked to monitor their physical activity by wearing a pedometer and recording the total steps walked every day.

Low Fat Diet plus exercise

Low carbohydrate diet plus exercise: Subjects were educated about a low carbohydrate diet and then followed for weight loss. They were also asked to monitor their physical activity by wearing a pedometer and recording the total steps walked every day.

Low Carbohydrate diet + Exercise

Ohio State University

Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk

A Randomized Comparison of a Low Fat or Low Carbohydrate Dietary Pattern for Weight Loss and Impact on Biomarkers Associated With Breast Cancer Risk in Overweight and Obese Premenopausal Women: Lifestyle Eating and Fitness

Electra Paskett

Associate Director for Population Sciences, Comprehensive Cancer Center, Ohio State University; Marion N. Rowley Professor of Cancer Research and Director, Division of Cancer Prevention and Control

skin neoplasms/carbohydrate

Preoperative Acetaminophen and Carbohydrate Loading

Clinical Validation of a Raman Spectroscope to Determine Hepatic Fat Content

Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA

Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk

Low Fat Diet to Prevent Disease Progression in Patients With Skin Cancer

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