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staphylococcal infections/albumin

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Therapeutic plasma exchange (TPE) has been used extensively for over 2 decades to treat a variety of autoimmune and congenital diseases and is now widely accepted. The primary objective of this study was to compare the clinical efficacy of two plasma exchange preparations, human serum protein (HSP)

Laboratory evaluation of the serum dilution test in serious staphylococcal infection.

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Four test media were studied to determine performance characteristics of serum dilution tests used to monitor antimicrobial therapy during serious Staphylococcus aureus infection being treated with highly protein-bound antibiotics. Serum inhibitory titers and serum bactericidal titers obtained with
In the process of staphylococcal infection in mice an increase in the number and functional activity of peritoneal, mesenterial and dermal basophils occurs. The preliminary activation of tissue basophils with equine serum albumin has favorable influence on the course of the infectious process,

Lactation stage, parity, and infection affecting somatic cells, electrical conductivity, and serum albumin in milk.

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Effects of stage of lactation and parity on cell concentration, electrical conductivity, and serum albumin concentration of milk from quarters of known infection status were examined. For quarters free from infection, somatic cell concentration rose from 80 to 160 x 10(3) cells/ml between 35 and

Fusidic acid binding to serum albumin and interaction with binding of bilirubin.

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Sodium fusidate, an antibiotic used in staphylococcal infections, is strongly bound to human serum albumin, competitively with bilirubin. It is given in molar amounts sufficient to occupy a considerable fraction of circulating albumin. In order to avoid a risk of bilirubin encephalopathy, induced by
The therapeutic effect of dye compounds with antibacterial activity was evaluated in a silkworm model of Staphylococcus aureus infection. Among 13 chromogenic agents that show antibacterial activity against S. aureus (MIC = 0.02 to 19 μg/mL), rifampicin had a therapeutic effect. The ED(50) value in
Fusidic acid is a natural product antibiotic used clinically, primarily against staphylococcal infections. It has also exhibited antimycobacterial activity against Mycobacterium species, including Mycobacterium tuberculosis (Mtb). Novel C-21 fusidic acid amides were synthesized
Vertebral osteomyelitis (VO) is a severe infection of the vertebral body and the adjacent disc space, where Staphylococcus aureus is most commonly isolated. The objective of this retrospective study was to determine risk factors for and compare outcome differences between de novo

Epinecidin-1 Protects against Methicillin Resistant Staphylococcus aureus Infection and Sepsis in Pyemia Pigs.

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Methicillin resistant Staphylococcus aureus (MRSA) may be found on the skin, nose, and throats of long-term hospitalized patients. While MRSA infections are usually minor, serious infections and death may occur in immunocompromised or diabetic patients, or after exposure of MRSA to blood.
The relationship between albumin or alpha 1-acid glycoprotein (AAG) levels and vancomycin (VCM) protein binding was studied in 44 serum samples from the 10 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection receiving VCM therapy. Eighty serum samples from 80 healthy subjects

An outbreak of methicillin-resistant Staphylococcus aureus infections related to central venous catheters for hemodialysis.

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OBJECTIVE To determine risk factors for hemodialysis catheter-related bloodstream infections (HCRBSIs) and investigate whether use of maximal sterile barrier precautions would prevent HCRBSIs. METHODS Tertiary-care medical center hemodialysis unit. METHODS Open trial with historical comparison and
Staphylococcus aureus is a human pathogen causing life-threatening diseases. The increasing prevalence of multidrug-resistant S. aureus infections is a global health concern, requiring development of novel therapeutic options. Peptidoglycan-degrading enzymes (peptidoglycan hydrolases,

Thrombospondin binds to Staphylococcus aureus and promotes staphylococcal adherence to surfaces.

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Bacterial adherence to surfaces is the determining first step in staphylococcal infections. Activated platelets mediate adherence of staphylococci to tissues during inflammation or infection; however, the molecular mechanisms of this interaction are not clearly understood. Thrombospondin, a large
The efficacy of intravenous immunoglobulin (IVIG) as prophylaxis for late sepsis was evaluated in a placebo-controlled, randomized, double-blind trial involving 240 infants of very low birth weight (less than 1,300 g). Each infant received a total of five doses of either IVIG (1 g/d) or an albumin

Adsorption of fibronectin onto polymethylmethacrylate and promotion of Staphylococcus aureus adherence.

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Recent data suggest that fibronectin may favor Staphylococcus aureus infection by promoting attachment to either injured tissues or implanted foreign bodies. We studied the quantitative adsorption of fibronectin onto polymethylmethacrylate (PMMA) cover slips by using a 125I-labeled preparation of
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