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Combinations of 10-propargyl-10-deazaaminopterin and taxols and methods of using same in the treatment of tumors
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BACKGROUND OF THE INVENTION
This application relates to a composition comprising 10-propargyl-10-deazaaminopterin and a taxol, and to methods of using this composition in the treatment of tumors.
10-Propargyl-10-deazaaminopterin ("10-propargyl-10dAM") is a member of a large class of compounds which
Taxol treatment of breast cancer
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FIELD OF THE INVENTION
The present invention relates to a method of treating patients who have breast cancer.
More particularly, the invention relates to treatment of patients with a taxol solution administered as a 96 hour continuous infusion every 21 days.
BACKGROUND OF THE INVENTION
Taxol is a
Composition for treating cancer via liposomal aerosol formulation containing taxol
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the field of pharmacology and cancer treatment. Specifically, the present invention provides formulations and methods for small particle aerosol delivery by inhalation of aqueous dispersions of liposomes
Method for effecting tumor regression with a low dose, short infusion taxol regimen
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FIELD OF THE INVENTION
The present invention is directed to methods of cancer treatment with taxol, and more particularly is directed to improvements in the administration of taxol in the treatment of cancer.
BACKGROUND OF THE INVENTION
Taxol is a natural occurring compound which has shown great
Taxol and epidermal growth factor used to enhance treatment of ovarian cancer
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FIELD OF THE INVENTION
This invention relates to cancer treatment and to augmentation of anti-neoplastic drug efficacy.
BACKGROUND OF THE INVENTION
Cisplatin (DDP) is one of the most widely used antineoplastic agents for the treatment of human ovarian cancer (Ozois and Young, Semin. Oncol.
Taxol production by a microbe
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TECHNICAL FIELD
The present invention relates to the use of one or more microorganisms to produce taxol (and related taxanes). The invention discloses the method of the discovery of said microorganisms, their isolation, screening for taxol production, growth requirements for taxol production, and
Taxol production by a microbe
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TECHNICAL FIELD
The present invention relates to the use of one or more microorganisms to produce taxol (and related taxanes). The invention discloses the method of the discovery of said microorganisms, their isolation, screening for taxol production, growth requirements for taxol production, and
Taxol production by a microbe
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TECHNICAL FIELD
The present invention relates to the use of one or more microorganisms to produce taxol (and related taxanes). The invention discloses the method of the discovery of said microorganisms, their isolation, screening for taxol production, growth requirements for taxol production, and
Taxol production by a microbe
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TECHNICAL FIELD
The present invention relates to the use of one or more microorganisms to produce taxol (and related taxanes). The invention discloses the method of the discovery of said microorganisms, their isolation, screening for taxol production, growth requirements for taxol production, and
Taxol production by a microbe
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TECHNICAL FIELD
The present invention relates to the use of one or more microorganisms to produce taxol (and related taxanes). The invention discloses the method of the discovery of said microorganisms, their isolation, screening for taxol production, growth requirements for taxol production, and
Taxol production by a microbe
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TECHNICAL FIELD
The present invention relates to the use of one or more microorganisms to produce taxol (and related taxanes). The invention discloses the method of the discovery of said microorganisms, their isolation, screening for taxol production, growth requirements for taxol production, and
Taxol resistance associated gene
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BACKGROUND OF THE INVENTION
Acquired drug resistance to currently available chemotherapeutic drugs is a major cause of failure of cancer treatment (Gottesman et al., 1993, Annu Rev. Biochem 62:385-427; Van Der Zee et al., 1995, Gynecologic Oncol. 58:165-178; Casazza et al., 1996, Cancer Treat. Res.
Liposome-encapsulated taxol, its preparation and its use
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BACKGROUND OF THE INVENTION
This appln. is a 371 of PCT/DE95/01163 filed Aug. 18, 1995.
The invention relates to liposome-encapsulated taxol, its preparation and its use. Areas, in which the invention can be used, are medicine and the pharmaceutical industry.
Taxol is a natural product, which occurs
Method for treating taxol side-effects with G-CSF
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TECHNICAL FIELD OF THE INVENTION
The present invention relates generally to an improved method for treating a host with taxol. More specifically, the present inventive method pertains to the treatment of cancerous tumors in humans, especially ovarian tumors, with taxol.
BACKGROUND OF THE
Method of preparing a taxol derivative
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BACKGROUND OF THE INVENTION
Taxol is a member of the taxane family of diterpenes, having the structure shown below: ##STR2##
The numbering system shown for taxol is that recommended by IUPAC (IUPAC, Commission on the Nomenclature of Organic Chemistry, 1978).
The chemistry of the potent anticancer
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