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[Vomiting associated with weight stagnation and convulsions: urea cycle disorder should be suspected].
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In some inherited metabolic diseases, in particular in urea cycle disorders, which are usually diagnosed in neonatal period or in childhood, vomiting is often the first symptom. We report a case of late revelation of urea cycle disorder in a 13 years old female patient hospitalized for convulsions
Neurological Etiologies and Pathophysiology of Cyclic Vomiting Syndrome.
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Cyclic vomiting syndrome is an idiopathic chronic periodic disorder of childhood which may persist into the adult years. Although cyclic vomiting syndrome is considered a central nervous system disorder, it is often managed by a pediatric gastroenterologist. The practitioner should not assume a
Vomiting, ataxia, and altered mental status in an adolescent: late-onset ornithine transcarbamylase deficiency.
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A case of a 13-year-old boy with protracted vomiting, ataxia, and altered mental status, ultimately diagnosed with late-onset ornithine transcarbamylase (OTC) deficiency, is presented. OTC deficiency is the most common urea cycle defect and typically is diagnosed in male infants with irritability,
Cisplatin-induced vomiting depends on circadian timing.
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We examined whether the clock time of cisplatin plus antiemetic and diuretic administration affects the amount of cisplatin-associated emesis and severity of renal toxicity. We treated 22 patients with urogenital cancer with two courses of chemotherapy containing 70 mg/m2 of cisplatin. Cisplatin
Relationship between Helicobacter pylori infection and vomiting induced by gastrointestinal cancer chemotherapy.
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BACKGROUND
Nausea and vomiting are the most common adverse reactions to chemotherapy.
OBJECTIVE
To discuss the relationship between Helicobacter pylori and chemotherapy-induced nausea and vomiting (CINV).
METHODS
A total of 112 patients with malignant tumours of the gastrointestinal tract was
Treatment of nausea and vomiting in pregnancy. When should it be treated and what can be safely taken?
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Nausea and vomiting are both common in early pregnancy. Most cases are mild and do not require treatment. However, persistent vomiting and severe nausea can progress to hyperemesis if the woman is unable to maintain adequate hydration, and fluid and electrolyte as well as nutritional status are
Effects of arginine treatment on nutrition, growth and urea cycle function in seven Japanese boys with late-onset ornithine transcarbamylase deficiency.
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BACKGROUND
The aim of this study was to investigate the effects of arginine on nutrition, growth and urea cycle function in boys with late-onset ornithine transcarbamylase deficiency (OTCD). Seven Japanese boys with late-onset OTCD enrolled in this study resumed arginine treatment after the
Citrulline for urea cycle disorders in Japan.
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BACKGROUND
The amino acid l-citrulline is used as a therapeutic agent for urea cycle disorders (UCD) including ornithine transcarbamylase deficiency (OTCD), carbamoyl phosphate synthetase I deficiency (CPSD), and N-acetylglutamate synthase deficiency. There are few reports, however, on the use of
Intra-amniotic prostaglandin F2alpha and urea for midtrimester abortion.
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Intra-amniotic prostaglandin F2alpha, in doses of 2.5 to 20 mg, combined with 80 gm of urea, was an effective, safe, simple, and economical midtrimester abortifacient in 115 patients. The mean abortal time, 15.8 hours, was significantly less than that in prior series in which intra-amniotic
Serum urea, creatinine and electrolyte status in patients presenting with acute gastroenteritis.
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The present study was undertaken to estimate the serum urea, creatinine and electrolyte status of patients presenting with acute gastroenteritis. Sixty patients who presented to Kathmandu Medical College and Teaching hospital from 15 June to 15 July 2005 with acute diarrhea with or without
The Use of 13 C-Urea Breath Test for Non-Invasive Diagnosis of Helicobacter pylori Infection in Comparison to Endoscopy and Stool Antigen Test
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Helicobacter pylori (H. pylori) can cause gastritis, peptic ulcer diseases and gastric carcinoma. Endoscopy as the gold standard method of diagnosis is an invasive procedure that might not be suitable in all scenarios. Therefore, this first study in Jordan aimed to assess the
Self-reported treatment-associated symptoms among patients with urea cycle disorders participating in glycerol phenylbutyrate clinical trials.
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BACKGROUND
Health care outcomes have been increasingly assessed through health-related quality of life (HRQoL) measures. While the introduction of nitrogen-scavenging medications has improved survival in patients with urea cycle disorders (UCDs), they are often associated with side effects that may
[Diagnosis and treatment of urea cycle disorders in adult patients].
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Urea cycle disorders (UCDs) are inborn errors of metabolism in which the clinical picture is mostly due to ammonia intoxication. UCD onset may be observed at any age. Acute decompensations of UCDs include neuro-psychiatric symptoms such as headache, confusion, convulsions, ataxia, agitation or
Intraamniotic urea for induction of midtrimester pregnancy termination: a further evaluation.
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Forty percent hyperosmolar urea solution was used intraamniotically to induce midtrimester pregnancy termination in 508 patients. The mean injection-abortion interval was 43.4 hours in those patients aborting within 7 days (85.8% of the total group); 76% of the group aborted within 72 hours.
Perioperative management of children with urea cycle disorders.
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