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Ureas and compositions thereof for treating cancer, inflammation, or a viral infection
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1. FIELD OF THE INVENTION
The present invention relates to novel carbamates, ureas, and pharmaceutically acceptable salts thereof; compositions comprising the carbamate, urea, or a pharmaceutically acceptable salt thereof; and methods for treating or preventing cancer, inflammation, or a viral
N-adamant-1-y1-N1-[4-chlorobenzothiazol-2-y1] urea useful in the treatment of inflammation and as an anticancer radiosensitizing agent
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FIELD OF THE INVENTION
This invention relates generally to N-adamant-1-yl-N'-[4-chlorobenzothiazol-2-yl] urea, pharmaceutical compositions comprising the same, and methods of using the same in the treatment of inflammation and as an anticancer radiosensitizing agent.
BACKGROUND OF THE INVENTION
The
Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity
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BACKGROUND OF THE PRESENT INVENTION
The present invention is novel compounds, which are derivatives of hydroxybenzylamine and as such are related to capsaicin. The present compounds have antiinflammatory activity for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel
Benzenesulphonate salt of a morpholine urea derivative for use as a CCR-3 antagonist in the treatment of inflammatory conditions
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is filed pursuant to 35 USC 371 as a United States National Phase Application of International Patent Application Serial No. PCT/EP03/03345 filed on 27 Mar. 2003, which claims priority from GB 0207432.6 filed on 28 Mar. 2002 in the United
Morpholinyl-urea derivatives for use in the treatment of inflammatory diseases
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is filed pursuant to 35 USC 371 as a United States National Phase Application of International Patent Application Serial No. PCT/EP03/03335 filed on 27 Mar. 2003, which claims priority from GB 0207434.2 filed on 28 Mar. 2002 and GB 0301608.6
Urea derivative or pharmacologically acceptable salt thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is the National Stage of International Patent Application No. PCT/JP2016/002557 filed May 26, 2016, which claims priority from Japanese Patent Application No. 2015-107227 filed May 27, 2015, the disclosures of each of which are incorporated
Heterocyclylcarbonyl substituted benzofuranyl-ureas
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The invention relates to heterocyclylcarbonyl substituted benzofuranyl-ureas, processes for their preparation and their use in medicaments.
It is known that the NADPH oxidase of phagocytes is the physiological source to the superoxide radical anion and reactive oxygen species derived therefrom which
N-(3-benzofuranyl)urea-derivatives
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The invention relates to N-(3-benzofuranyl)urea-derivatives, processes for their preparation and their use in medicaments.
It is known that the NADPH oxidase of phagocytes is the physiological source to the superoxide radical anion and reactive oxygen species derived therefrom which are important in
N-(3-benzofuranyl) urea-derivatives
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The invention relates to N-(3-benzofuranyl)urea-derivatives, processes for their preparation and their use in medicaments.
It is known that the NADPH oxidase of phagocytes is the physiological source to the superoxide radical anion and reactive oxygen species derived therefrom which are important in
Tri-substituted ureas as cytokine inhibitors
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FIELD OF THE INVENTION
The present invention relates to 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising
Tri-substituted ureas as cytokine inhibitors
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FIELD OF THE INVENTION
The present invention relates to 1-(N-substituted aryl)-1-N-(2-substituted pyrimidin-4-yl)-3-N-(alkyl or substituted alkyl) ureas which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease
Hyaluronic acid-urea pharmaceutical compositions and uses
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BACKGROUND OF THE INVENTION
The present invention concerns pharmaceutical compositions which include urea and hyaluronic acid or derivatives of hyaluronic acid. The present invention further concerns methods of treating disease of the cutis, anorectal epithelium and rectal mucosa employing the
Hyaluronic acid-urea pharmaceutical compositions and uses
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BACKGROUND OF THE INVENTION
The present invention concerns pharmaceutical compositions which include urea and hyaluronic acid or derivatives of hyaluronic acid. The present invention further concerns methods of treating disease of the cutis, anorectal epithelium and rectal mucosa employing the
Hyaluronic acid-urea pharmaceutical compositions and uses
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BACKGROUND OF THE INVENTION
The present invention concerns pharmaceutical compositions which include urea and hyaluronic acid or derivatives of hyaluronic acid. The present invention further concerns methods of treating disease of the cutis, anorectal epithelium and rectal mucosa employing the
Hyaluronic acid-urea pharmaceutical compositions and uses
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BACKGROUND OF THE INVENTION
The present invention concerns pharmaceutical compositions which include urea and hyaluronic acid or derivatives of hyaluronic acid. The present invention further concerns methods of treating disease of the cutis, anorectal epithelium and rectal mucosa employing the
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