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uronic acid/radang
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[On the uronic acid metabolism in blood in healthy patients and patients with degenerative and inflammatory joint diseases].
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Urinary excretion of connective tissue metabolites under the influence of a new non-steroidal anti-inflammatory agent in adjuvant induced arthritis.
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The therapeutic effect of boswellic acids and salai guggal in adjuvant induced arthritic rats in relation to urinary excretion of connective tissue metabolites viz. hydroxyproline, hexosamine and uronic acid was thoroughly investigated. Compared to controls, the arthritic animals showed an increase
Novel Aeruginosin-865 from Nostoc sp. as a potent anti-inflammatory agent.
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Aeruginosin-865 (Aer-865), isolated from terrestrial cyanobacterium Nostoc sp. Lukešová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety, and is the first aeruginosin to be found in the genus Nostoc. Mass spectrometry, chemical and spectroscopic
Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from Ecklonia cava.
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Enzymatic extraction has been successfully used for extracting numerous biologically active compounds from a wide variety of seaweeds. In this study, we found that enzymatic extraction of the fucoidan from Ecklonia cava may be more advantageous than water extraction. Therefore, we studied the E.
Studies on the metabolism of glycosaminoglycans under the influence of new herbal anti-inflammatory agents.
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The in vivo effect of an herbal based, non-steroidal anti-inflammatory product, salai guggal, prepared from the gum resin exudate of Boswellia serrata and its active principle "boswellic acids" on glycosaminoglycan metabolism has been studied in male albino rats. The biosynthesis of sulfated
Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice.
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Neutrophil recruitment and extravasation at sites of inflammation provide a mechanism for host defense. We showed previously that heparan sulfate, a type of sulfated glycosaminoglycan, facilitates neutrophil recruitment based on the reduction of neutrophil infiltration in mice in which the overall
Structure Characterization of Honey-Processed Astragalus Polysaccharides and Its Anti-Inflammatory Activity In Vitro.
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Honey-processed Astragalus is a dosage form of Radix Astragalus mixed with honey by a traditional Chinese medicine processing method which strengthens the tonic effect. Astragalus polysaccharide (APS), perform its immunomodulatory effects by relying on the tonic effect of Radix Astragalus,
[Anti-inflammatory effect of Cu-Zn superoxide dismutase on carrageenin-induced arthritis in rabbits].
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Anti-arthritic action of superoxide dismutase (SOD) was studied in rabbits. Arthritis was induced by intraarticular injections of lambda-carrageenin (1%, 1 ml) into the knee joint weekly for two weeks. In this experimental arthritis, acid phosphatase activity, quantities of protein, uronic acid and
Physicochemical characteristics and anti-inflammatory activities of antrodan, a novel glycoprotein isolated from Antrodia cinnamomea mycelia.
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Antrodia cinnamomea (AC) is a unique fungus found inhabiting the rotten wood of Cinnamomum kanehirai. A submerged liquid culture of AC has been developed and its bioproducts have been used to meet the market demand for natural fruiting bodies. AC exhibits anti-inflammatory, antitumor, antioxidant,
Enzymatic Extraction, Purification, and Characterization of Polysaccharides from Penthorum chinense Pursh: Natural Antioxidant and Anti-Inflammatory.
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Penthorum chinense Pursh (PCP) is a kind of functional food or medicine for liver protection. In the present work, Plackett-Burman design, steepest ascent method, and response surface methodology (RSM) were employed to obtain maximum total sugar yield. The experimental yield of 6.91%
Targeted inhibition of tumor survival, metastasis and angiogenesis by Acacia ferruginea mediated regulation of VEGF, inflammatory mediators, cytokine profile and inhibition of transcription factor activation.
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Acacia ferruginea extract (AFE) was studied for anti-metastasis/-angiogenesis activity against B16F-10 melanoma cells in C57BL/6 mice. In vitro cytotoxicity of AFE was first screened using MTT assay and it was shown to inhibit B16F-10 cells with IC50 value of 52.94 μg/ml. Anti-metastatic activity of
The effect of chronic inflammation on gingival connective tissue proteoglycans and hyaluronic acid.
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Proteoglycans have been isolated and analysed from extracts of normal and chronically inflamed human gingiva in order to determine the effects of chronic inflammation on these important soft connective tissue extracellular macromolecules. The uronic acid content of glycosaminoglycans isolated by
Isolation, structure identification and anti-inflammatory activity of a polysaccharide from Phragmites rhizoma
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Phragmites rhizoma (PR) is comprised of polysaccharides as its main active component. Currently, there are few studies on polysaccharides from PR, especially in purification and structure. In this study, an acidic polysaccharide (PRP-2) was obtained from PR by ultrasonic assisted extraction and
Development of rhamnose-rich hydrogels based on sulfated xylorhamno-uronic acid toward wound healing applications.
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An array of biological properties is demonstrated in the category of extracts broadly known as ulvans, including antibacterial, anti-inflammatory and anti-coagulant activities. However, the development of this category in biomedical applications is limited due to high structural variability across
In vivo efficiency of the collagen coated nanofibrous scaffold and their effect on growth factors and pro-inflammatory cytokines in wound healing.
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Exploring the importance of nanofibrous scaffold with traditionally important medicine as a wound dressing material prevents infection and aids in faster healing of wounds. In the present study, the Collagen (COL) from the marine fish skin was extracted and employed for coating the
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