varicose veins/phosphatase

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Prevalence and associated factors with esophageal varices in early primary biliary cirrhosis.

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OBJECTIVE Recent routine testing for anti-mitochondrial antibodies has increased the number of patients with early primary biliary cirrhosis (PBC). The prevalence and clinical significance of esophageal varices in those patients remains obscure. METHODS A systematic cohort analysis of 256 PBC

Immunological response and oesophageal varices in PBC.

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A retrospective study was made of the clinical features, especially oesophageal varices, of 93 patients with PBC. The 5 year survival rate of asymptomatic PBC patients was 88.7% and that of symptomatic PBC was 43.7%. The 5 year survival rate of the group with oesophageal varices was 44.0% and that

[Calcium determination, enzyme biochemical and electron microscopy studies of saphenous veins in patients with coronary sclerosis or varicose veins].

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In patients undergoing aortic-coronary bypass operations, essentially similar ultrastructural changes are found both in the fragments removed from the coronary arteries and in veins from the saphenous system that are about to be used as autografts. The most important changes involve the intima and

Lysosomal enzymes and superoxide production in polymorphonuclear leukocytes of patients with primary varicose veins.

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In order to clarify the role of reactive oxygen species and lysosomal enzymes in the etiopathogenesis of varicose veins, the investigation of their activities in serum and peripheral neutrophils of 17 patients with primary varicose veins was done. The mean activities of acid phosphatase,

[Histochemical comparison of the enzyme profiles of healthy veins and varicose veins].

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In the context of studies bearing on the enzymatic activity in healthy veins and varicose veins, sample sections of veins were excised in eight patients with primary varices of the long saphenous vein. The veins were subjected to histochemical methods for identifying enzymes. The histochemical

A case of asymptomatic primary biliary cirrhosis with an initial presenting feature of localized gastric varices.

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A case of asymptomatic primary biliary cirrhosis (PBC) with an initial presenting feature of localized gastric varices is reported. The patient, 64 years old female, underwent a barium meal examination because of ill-defined abdominal complaints and was found to have gastric varices localized at the

Bile duct varices or "pseudo-cholangiocarcinoma sign" in portal hypertension due to cavernous transformation of the portal vein.

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A total of 832 patients with portal hypertension resulting from different etiology was studied by ultrasonograph as a screening test. In 17 of the 832 patients, cavernous transformation of the portal vein was detected by means of ultrasonography. We have prospectively studied these 17 patients, and

[Prediction of bleeding risks and death in cirrhosis based on hemodynamic and metabolic variables. A study of patients with esophageal varices without previous bleeding].

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As identification of patients with liver cirrhosis who are at risk of bleeding or death is essential in terms of prophylaxis, we have determined the prognostic influence of various patient characteristics on risk of bleeding and death. Fifty-five cirrhotic patients with oesophageal varices without

Serum fibrosis markers can detect large oesophageal varices with a high accuracy.

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OBJECTIVE The aim of this study was to determine the value of serum fibrosis markers for the diagnosis of oesophageal varices in alcoholic patients. METHODS Fifty-four sets of clinical and biochemical data, including serum markers of fibrosis, obtained from 146 heavy alcohol drinkers (106 men, 40

[Two cases of esophageal varices complication after hepatic arterial infusion chemotherapy (HAI) for metastatic liver tumor].

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Mild liver dysfunction is a well-known complication of HAI, but it has been thought to be transient and reversible in most cases. In the case, of metastatic liver disease, in particular, HAI has been performed safely because liver function is normal for the most part. We encountered 2 cases of

Bleeding oesophageal varices and hepatic dysfunction in adult polycystic kidney disease.

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A patient with adult polycystic liver and kidney disease presented with haematemesis and melaena and was found to have raised serum creatinine, aspartate transaminase, and alkaline phosphatase values; hypoalbuminaemia; and a prolonged prothrombin ratio. She also had oesophageal varices. With

A validated clinical tool for the prediction of varices in PBC: the Newcastle Varices in PBC Score.

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OBJECTIVE Gastro-oesophageal varices (GOV) can occur in early stage primary biliary cirrhosis (PBC), making it difficult to identify the appropriate time to begin screening with oesophageo-gastro-duodenoscopy (OGD). Our aim was to develop and validate a clinical tool to predict the probability of

Prognostic variables in patients with cirrhosis and oesophageal varices without prior bleeding.

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As identification of patients at risk of bleeding or death is essential for prophylaxis, we determined the prognostic influence of various patient characteristics on the risk of bleeding and death. Fifty-five patients with cirrhosis and oesophageal varices without previous bleeding were included in

A clinical and molecular review of ubiquitous glucose-6-phosphatase deficiency caused by G6PC3 mutations.

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The G6PC3 gene encodes the ubiquitously expressed glucose-6-phosphatase enzyme (G-6-Pase β or G-6-Pase 3 or G6PC3). Bi-allelic G6PC3 mutations cause a multi-system autosomal recessive disorder of G6PC3 deficiency (also called severe congenital neutropenia type 4, MIM 612541). To date, at least 57

Cirrhosis following single anastomosis duodeno-ileal switch: A case report.

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BACKGROUND Single anastomosis duodeno-ileal switch (SADI-S) involves a single, loop duodeno-ileal anastomosis with omission of the traditional Roux-en-Y distal ileo-ileal anastomosis. Not much has been published on the complications of SADI-S. METHODS The patient is a 40 year-old male who underwent

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