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International Journal of Dentistry 2019

Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains.

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Krækjan er vistuð á klemmuspjaldið
Frank Mayta-Tovalino
Eloy Gamboa
Richard Sánchez
Jorge Rios
Ramín Medina
Martín García
Jhonn Asencios

Lykilorð

Útdráttur

Objectives
To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains.

Methods
The sample was calculated using the mean comparison formula, obtaining wells (n = 12) for each of the strains evaluated: S. mutans, E. faecalis, Actinomyces, Lactobacillus, C. albicans, S. sanguinis, and S. oralis. The antibacterial activity of the dentifrice was evaluated by the direct contact technique.

Results
It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of S. mutans 21.0 ± 1.8, E. faecalis 16.3 ± 3.9, Actinomyces 22.1 ± 1.3, and Lactobacillus 21.0 ± 1.3. However, in comparison with other strains such as C. albicans, S. sanguinis, and S. oralis, the peel-based dendrifrice of Passiflora mollissima obtained the highest antimicrobial activity.

Conclusion
The experimental dentifrice based on Passiflora mollissima had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.

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