[Peculiarity of the antioxidant action of the extract from Aronia melanocarpa leaves antioxidant on the brain].

The antioxidant action of the extract from Aronia melanocarpa leaves on the brain was investigated. The intraperitoneal injection of extract in the dose of 0.2 g/kg prevented manifestations of oxidative stress in the brain induced by immobilization of rats. In vitro experiments revealed that the extract decreased intensity of ascorbate--and H2O2 -induced lipid and protein peroxidation in the brain homogenates. The most effect of the extract on ascorbate--induced lipid peroxidation was found in the postmitochondrial fraction of brain homogenate.