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Effects of ondansetron and granisetron on postoperative nausea and vomiting in adult patients undergoing laparoscopic cholecystectomy: a randomized, double-blind, placebo-controlled clinical trial.

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BACKGROUND Postoperative nausea and vomiting (PONV) are common and potentially distressing adverse events (AEs) associated with surgery and anesthesia. In patients undergoing laparoscopic cholecystectomy (LC) without antiemetic prophylaxis, the incidence of PONV can be as high as 72%. OBJECTIVE The

Radiology case of the month. Nausea, vomiting, and diarrhea in a patient with hepatitis C and acquired immunodeficiency syndrome (AIDS). Diffuse, severe gastric-wall thickening, consistent with edema.

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The patient is a 42-year-old male with a past medical history of HIV/AIDS (his most recent CD4 count, four months before admission, was 19) and hepatitis C who presented to the Emergency Department complaining of one week of persistent nausea, vomiting, and diarrhea. His admit labs were as follows:

Stratified, randomized, double-blind comparison of intravenous ondansetron administered as a multiple-dose regimen versus two single-dose regimens in the prevention of cisplatin-induced nausea and vomiting.

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OBJECTIVE This study compares the efficacy and safety of two single-dose regimens with the approved three-dose regimen of ondansetron in the prevention of cisplatin-induced emesis. METHODS This multicenter study was a stratified, randomized, double-blind, and parallel group design.

Adverse effects of rifampicin in dogs and serum alanine aminotransferase monitoring recommendations based on a retrospective study of 344 dogs.

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BACKGROUND Rifampicin has been reported to have potent activity against Staphylococci, including meticillin-resistant Staphylococcus pseudintermedius. There is limited documented information regarding adverse effects and recommendations for serum biochemistry monitoring. OBJECTIVE The aims of this

Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial.

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BACKGROUND Palonosetron is a second-generation 5-hydroxytryptamine 3 (5-HT(3))-receptor antagonist that has shown better efficacy than ondansetron and dolasetron in preventing chemotherapy-induced nausea and vomiting (CINV) in patients receiving moderately emetogenic chemotherapy, and similar

A controlled trial of tacrine in Alzheimer's disease. The Tacrine Study Group.

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OBJECTIVE To compare efficacy and safety of tacrine hydrochloride with placebo in patients with probable Alzheimer's disease. METHODS A 12-week, double-blind, placebo-controlled, parallel-group study. METHODS Outpatients at 23 centers. METHODS Men and women with probable Alzheimer's disease, at

Establishment and Application of Early Risk Stratification Method for Acute Abdominal Pain in Adults.

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BACKGROUND Acute abdominal pain is a common symptom of emergency patients. The severity was always evaluated based on physicians' clinical experience. The aim of this study was to establish an early risk stratification method (ERSM) for addressing adults with acute abdominal pain, which would guide

Occurrence of abscesses during treatment with pazopanib in metastatic renal cancer: a case report.

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Pazopanib is a multitarget tyrosine kinase inhibitor used in the treatment of renal cancer and soft tissue sarcoma. Its use is commonly associated with a number of side effects, such as hemorrhagic diathesis, neutropenia, leukopenia, thrombocytopenia, nausea, vomiting, abdominal pain,

Coronavirus Disease 2019 versus Influenza A in Children: An Observational Control Study in China

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This study aimed to understand the differences in clinical, epidemiological, and laboratory features between the new coronavirus disease 2019 (COVID-2019) and influenza A in children. Data of 23 hospitalized children with COVID-19 (9 boys, 5.7 ± 3.8 years old) were compared with age- and sex-matched

Treatment-related adverse effects with TKIs in patients with advanced or radioiodine refractory differentiated thyroid carcinoma: a systematic review and meta-analysis.

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Tyrosine kinase inhibitors (TKIs) have been administered to advanced or radio-iodine refractory differentiated thyroid carcinoma (RR-DTC) patients for years. We performed a pooled analysis to explore the frequency of severe adverse effects in advanced or RR-DTC patients treated with

Pathophysiologic and immunologic changes in a canine endotoxemia over a period of 24 hours.

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In this study, the pathophysiologic and immunologic parameters from a 24-hr of canine endotoxemia model by lipopolysaccharide (LPS) infusion were evaluated. For that, twelve healthy beagles received a continuous 24-hr IV infusion of low dose LPS (10 µg/kg/h, from Escherichia coli serotype O111:B4)

Retrospective evaluation of xylitol ingestion in dogs: 192 cases (2007-2012).

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OBJECTIVE To summarize the signalment, clinical signs, prevalence of decreased blood glucose concentration (BG), prevalence of increased liver values, treatment, and outcome in dogs known to have ingested xylitol. METHODS Retrospective study from December 2007 to February 2012 SETTING: Three

Human infection due to Ebola virus, subtype Côte d'Ivoire: clinical and biologic presentation.

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In November 1994 after 15 years of epidemiologic silence, Ebola virus reemerged in Africa and, for the first time, in West Africa. In Côte d'Ivoire, a 34-year-old female ethologist was infected while conducting a necropsy on a wild chimpanzee. Eight days later, the patient developed a syndrome that

The in vitro interactions and in vivo efficacy of atovaquone and proguanil against Babesia gibsoni infection in dogs.

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In vitro interactions between atovaquone (ATV) and proguanil (PG) against Babesia gibsoni and the clinical efficacy of this combination therapy using Malarone(®) which is the antimalarial drug containing ATV and PG were evaluated. This combination showed synergism against uncloned wild-type and

Acute liver failure in two dogs following ingestion of cheese tree (Glochidion ferdinandi) roots.

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To describe the management and resolution of acute liver failure (ALF) in two dogs following ingestion of cheese tree (Glochidion ferdinandi) roots.

CASE SUMMARIES

A 2-year-old male entire Bullmastiff and a 5-year-old female neutered German Shepherd

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