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anticholinergic/hitasótt

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OBJECTIVE To determine the effect of soman on stress induced hyperthermia and the influence of central and peripheral cholinergic antagonists. METHODS Effects of subcutaneous injection of soman, scopolamine, methylscopolamine and pyridostigmine on stress-induced hyperthermia were observed in rats by

[Fever, large eyes and confusion; the anticholinergic syndrome].

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A 52-year-old woman was in a confused state and had difficulty walking and swallowing, as well as dysarthria. That same day she had consumed some berries, which she thought were bilberries, but she had instead eaten Atropa belladonna (deadly nightshade). She made a spontaneous and full recovery

Anticholinergic premedication-induced fever in paediatric ambulatory ketamine anaesthesia.

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OBJECTIVE A randomized, double-blind, prospective study to evaluate the effect of anticholinergic drugs on thermoregulation in paediatric patients undergoing ambulatory anaesthesia with ketamine. METHODS Patients were randomized to receive either 0.005 mg/kg glycopyrrolate or the equivalent volume
The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) Med Watch program (800-FDA-1088). If you have reported an interesting, preventable ADR to Med

[Fever, large eyes and confusion; the anticholinergic syndrome].

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[Fever, large eyes and confusion; the anticholinergic syndrome].

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[Fever, large eyes and confusion; the anticholinergic syndrome].

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[Fever, large eyes and confusion; the anticholinergic syndrome].

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Clozapine and Fever: A Case of Continued Therapy With Clozapine.

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Clozapine is a major atypical antipsychotic drug used in treatment-resistant schizophrenia (Patel and Allin. Ther Adv Psychopharmacol 2011;1:25-29). It interferes with dopamine binding to D1, D2, D3, and D5 receptors but has high affinity to D4. It also has an anticholinergic effect and antagonizes

Bench-to-bedside review: mechanisms and management of hyperthermia due to toxicity.

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Body temperature can be severely disturbed by drugs capable of altering the balance between heat production and dissipation. If not treated aggressively, these events may become rapidly fatal. Several toxins can induce such non-infection-based temperature disturbances through different underlying

[Central anticholinergic syndrome during postoperative period].

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The central anticholinergic syndrome (CAS) includes central signs (somnolence, confusion, amnesia, agitation, hallucinations, dysarthria, ataxia, delirium, stupor, coma) and peripheral signs (dry mouth, dry skin, tachycardia, visual disturbances and difficulty in micturition). It occurs when central

Effect of neurohumoral modulators on the morphine-induced hyperthermia in non-tolerant rats.

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Wistar rats from one supplier have been shown to exhibit the atypical body temperature responses to morphine. In contrast to commonly used rats, in which morphine induced dose-dependent changes in body temperature, the initial administration of morphine (5, 10, 20, and 40 mg/kg, s.c.) to rats of

Adverse drug reactions resulting in hyperthermia in the intensive care unit.

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Hyperthermia is frequently seen in the intensive care setting and is associated with significant morbidity and mortality. It is often initially misdiagnosed as fever associated with infection. Atypical presentations of classic syndromes are common. Clinical suspicion is the key to diagnosis. Adverse

[Malignant hyperthermia syndrome in the intensive care unit : Differential diagnosis and acute measures].

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Malignant hyperthermia is a life-threatening disease caused by derangement of the autonomic nerve system and hypermetabolism of the peripheral musculature. Commonly body core temperatures of more than 40 °C will be found in this disease which is caused mostly by psychopharmacological drugs like
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