artemether/niðurgangur

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Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial.

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BACKGROUND The efficacy of artemisinin-based combination therapy has already been demonstrated in a number of studies all over the world, and some of them can be regarded as comparably effective. Ease of administration of anti-malarial treatments with shorter courses and fewer tablets may be key

Intramuscular artemether in female patients with uncomplicated falciparum malaria.

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Thirty-three female patients suffering from acute uncomplicated falciparum malaria were treated with intramuscular artemether for 5 days during May-October 1990. Fourteen patients received 160 mg as an initial dose, followed by 80 mg daily for 4 days. Nineteen patients with low body weight (mean

Efficacy of a novel sublingual spray formulation of artemether in African children with Plasmodium falciparum malaria.

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The efficacy of sublingual artemether (ArTiMist) was investigated in two studies. In study 1, 31 children were randomized to sublingual artemether (n = 16) or intravenous (i.v.) quinine (n = 15). In study 2, 151 children were randomized to sublingual artemether (n = 77) or i.v. quinine (n = 74). For

Population pharmacokinetics and clinical response for artemether-lumefantrine in pregnant and nonpregnant women with uncomplicated Plasmodium falciparum malaria in Tanzania.

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Artemether-lumefantrine (AL) is the first-line treatment for uncomplicated malaria in the second and third trimesters of pregnancy. Its efficacy during pregnancy has recently been challenged due to altered pharmacokinetic (PK) properties in this vulnerable group. The aim of this study was to

[Clinical analysis of 91 cases of imported falciparum malaria from Africa].

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OBJECTIVE To explore the clinical characteristics, early diagnosis, and treatment of patients with imported falciparum malaria from Africa. METHODS The clinical data of 91 imported falciparum malaria cases were analyzed by retrospective study. RESULTS All the 91 cases had the history of mosquito

Does access to credit services influence availability of essential child medicines and licensing status among private medicine retail outlets in Uganda?

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BACKGROUND Despite making great progress in reducing under five mortality in the last three decades. Uganda still ranks high among countries with the highest under five mortality rates. More than a third (36%) of these deaths are caused by pneumonia (15%), malaria (12%), or diarrhea (9%). For many

Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis.

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BACKGROUND The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new artemisinin-based combination therapy (ACT). We present an individual patient data analysis of efficacy and tolerability in acute uncomplicated falciparum malaria, from seven published

Development of Resistance Against Mefloquine Prophylaxis in Peace-Keeping Forces in the Central African Republic

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Objective To record the frequency of malaria-like symptoms in patients who have been given mefloquine as chemoprophylaxis and to determine the effectiveness of antimalarials against these symptoms. Methodology It was an observational study that took place at a United Nations Level 1 hospital,

Malaria in Egypt, Saudi Arabia and Yemen: a clinical pilot study.

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Imported malaria is a health problem and needs continuous monitoring as many clinicians are not aware of it. In Yemen malaria is the main public health problem. Malaria cases were 16 in Almaza Military Fever Hospital, Cairo, 53 in Saudi Hospital at Pilgrimage, Yemen and in Saber Hospital at Aden,

Management of Childhood Infections in Poorly Planned Urban Settlements in Kampala and Wakiso Districts of Uganda

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The main objective of this study was to assess the management of childhood infections in high-density poorly planned urban areas of Kampala and Wakiso districts in Uganda, to develop a strategy to deliver integrated community case management (iCCM) of childhood illness services. A total of 72

Availability and utilization of the WHO recommended priority lifesaving medicines for under five-year old children in public health facilities in Uganda: a cross-sectional survey.

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OBJECTIVE To explore the availability and utilization of the World Health Organization (WHO) recommended priority life-saving medicines for children under five in public health facilities in Uganda. METHODS We conducted a cross sectional survey in 32 lower level public facilities in Jinja district

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