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blister/albumin

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Apart from the well-known sulfur mustard (SM), additional sulfur-containing blistering chemical warfare agents exist. Sesquimustard (Q) is one of them and five times more blistering than SM. It is a common impurity in mustard mixtures and regularly found in old munitions but can also be used in pure

Passage of albumin from plasma to suction skin blisters.

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To study the transvascular passage of albumin from the plasma to the skin interstitium, suction blisters were developed on the abdominal skin of six young, healthy male volunteers. Fifteen minutes after the blisters had been formed and the suction had been stopped, 125I-albumin was injected

[Studies on the binding capacity of albumins in the skin of skin blisters].

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Crystal-clear blister fluid with low albumin concentration during toxic epidermal necrolysis.

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Experience with an albumin-glutaraldehyde tissue adhesive in sealing air leaks after bullectomy.

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BACKGROUND The purpose of this study was to evaluate the effectiveness of an albumin-glutaraldehyde tissue adhesive (BioGlue Surgical Adhesive) in preventing air leaks after bullectomy. METHODS Between January 1999 and June 2002, BioGlue was applied over the staple or suture lines of 21 consecutive

Human anti-laminin 5 autoantibodies induce subepidermal blisters in an experimental human skin graft model.

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Patients with one form of cicatricial pemphigoid have IgG antibasement membrane autoantibodies against laminin 5 (alpha3beta3gamma2). Although passive transfer of rabbit anti-laminin 5 IgG to neonatal mice has been shown to induce subepidermal blisters that mimic those in patients, it has not been

Human plasma and skin blister fluid levels of griseofulvin following a single oral dose.

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Griseofulvin and 6-demethylgriseofulvin (6-DMG) in plasma, suction blister fluid (SBF) and cantharides blister fluid (CBF) and urinary excretion of 6-DMG, were evaluated following administration of single oral doses of an ultramicrosize and a microsize formulation of griseofulvin to 6 healthy
The wick technique and the blister suction technique are the most common methods for sampling of subcutaneous interstitial tissue fluid in man. The blister suction technique has the advantage of being less invasive than the wick technique, but the reliability of this method is still controversial.

Alteration of lipoproteins of suction blister fluid by UV radiation.

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Suction blister fluid is a good representative of the interstitial fluid feeding the epidermal cells. Lipoproteins contained in the suction blister fluid of healthy volunteers are readily photo-oxidized by UV radiation in the wavelength range 290-385 nm. Absorbed light doses equivalent to one

In vivo and in vitro evidence for autocrine DCoH/HNF-1alpha transcription of albumin in the human epidermis.

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The presence of albumin in the human epidermis has been reported more than a decade ago, but until now, it was assumed that this protein is synthesized in the liver and transported to the avascular skin. To our knowledge, transcription of albumin in the human epidermis was never considered. In this

Blister fluid composition in a pediatric patient with toxic epidermal necrolysis.

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Toxic epidermal necrolysis (TEN) is a rare life-threatening disease mostly related to drug ingestion. Apoptotic keratinocytes lead to separation of the epidermis from dermis and widespread blistering of the skin. This case is a pediatric patient with a seizure disorder who developed TEN after
OBJECTIVE Intravenous immunoglobulin (IVIg) is a solution of globulins containing antibodies derived from pooled human plasma of donors and used in the treatment of a number of immune deficiencies and autoimmune diseases. However, several investigators have reported biochemical alterations with use
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