A clear aqueous formulation for topical application in the oral cavity of humans to treat leukoplakia contains water, .beta.-carotene, a water miscible polyol, an unsaturated fatty acid ester, and a surfactant, preferably polyethoxylated castor oil. The formulation preferably also contains a pharmaceutically acceptable anti-oxidant, preferably d-alpha-tocopherol (vitamin E), and is in the form of an oral rinse or as a gel well suited for spreading on gums or other parts of the oral cavity. The formulation is applied in a gel form on a substantially regular daily basis to areas in the oral cavity where leukoplakia lesions are present. Persistent application of the gel results in substantial diminution or total elimination of the leukoplakia lesions.

Micelle Products, Inc.

Clear micellized formulations of .beta.-carotene and method of treating leukoplakia

A clear aqueous formulation for topical application in the oral cavity of humans to treat leukoplakia contains water, .beta.-carotene, a water miscible polyol, an unsaturated fatty acid ester, and a surfactant, preferably polyethoxylated castor oil or POE(20) sorbitan monooleate. The formulation preferably also contains a pharmaceutically acceptable anti-oxidant, preferably d-alpha-tocopherol (vitamin E), and is in the form of an oral rinse or as a gel well suited for spreading on gums or other parts of the oral cavity. The formulation is applied in a gel form on a substantially regular daily basis to areas in the oral cavity where leukoplakia lesions are present. Persistent application of the gel results in substantial diminution or total elimination of the leukoplakia lesions.

Food compositions, oral compositions and pharmaceutical compositions for preventing or treating periodontosis, the compositions comprising (A) one or more extracts containing natural polyphenol; and (B) one or more members selected from the group consisting of vitamin C, vitamin E, vitamin A and beta-carotene; and methods for preventing or treating periodontosis using the above compositions.

Sunstar Inc.

Food compositions, compositions for oral cavity and medicinal compositions for preventing or treating periodontosis and method for preventing or treating periodontosis

Disclosed in the present invention are a composition containing lutein/lutein ester and applications thereof. Components of the composition containing lutein/lutein ester comprise lutein/lutein ester, .beta.-carotene and a pharmaceutically acceptable carrier. The weight ratio of lutein/lutein ester to .beta.-carotene is 1:0.1-100. In the present invention, by cooperatively using lutein/lutein ester and .beta.-carotene and using auxiliary natural healthy ingredients, the dosage form of an orally disintegrating tablet is prepared. The orally disintegrating tablet is absorbed through the oral cavity, has fast effectiveness and small first-pass effect, reduces damage of gastric acid to lutein/lutein ester, has high bioavailability, and has the characteristics of nutritional and health-care effects, good mouthfeel and fast absorption. By eating the product, visual power can be obviously enhanced, the ocular blood flow is increased, and eye muscle fatigue is alleviated, and accordingly the morbidities of cataract, senile niacula lutea retinae lesion and adolescent myopia are reduced.

carotene/dental caries

Clear micellized formulations of .beta.-carotene and method of treating leukoplakia

Clear micellized formulations of .beta.-carotene and method of treating leukoplakia

Food compositions, compositions for oral cavity and medicinal compositions for preventing or treating periodontosis and method for preventing or treating periodontosis

Composition containing lutein/lutein ester and applications thereof

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