embolism/phosphatase

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Greinar Klínískar rannsóknirEinkaleyfi

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INCREASED SERUM ACID PHOSPHATASE AFTER ARTERIAL EMBOLISM.

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Increased γ-glutamyl transferase levels predict early mortality in patients with acute pulmonary embolism.

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BACKGROUND Increased γ-glutamyl transferase (GGT) level is associated with increased oxidative stress, all-cause mortality, the development of cardiovascular disease, and metabolic syndrome. However, its role in acute pulmonary embolism (PE) is unknown. In this study, we aimed to investigate the

[Renal artery embolism].

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OBJECTIVE To report a case of renal artery embolism. To review the clinical, diagnostic and therapeutic features of this disease interesting for the urologist. RESULTS Case of a 47 year old male with history of cardiovascular disease who presents in the emergency room with left flank pain.

Cholesterol embolism of bone marrow clinically masquerading as systemic or metastatic tumor.

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A case of cholesterol embolism of bone marrow, concerning the pelvis and lumbar region and clinically masquerading as systemic disease or metastatic tumor, is reported in an 82-year-old man hospitalized for acute onset of reddish purple nodules on the legs and toes, intense myalgia and dorsal

Lithium-induced activation of Akt and CaM kinase II contributes to its neuroprotective action in a rat microsphere embolism model.

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Lithium used in bipolar mood disorder therapy protects neurons from brain ischemic cell death. Here, we documented that lithium administration under microsphere-embolism (ME)-induced brain ischemia restored decreased protein kinase B (Akt) and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)

Renal artery embolism: clinical features and long-term follow-up of 17 cases.

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Spontaneous renal artery embolism is not rare, but a correct diagnosis and appropriate treatment are often delayed. Clinical features and follow-up of 17 cases are reported. Cardiac disease or arrhythmias pre-existed in 16 patients. Initial symptoms included flank pain (seven cases), abdominal or

[Value and diagnostic significance of serum lactic dehydrogenase in internal medicine (author's transl)].

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Among 2175 patients seen over the last three years in a non-specialized department of internal medicine with no intensive care unit, 100 had supranormal serum lactic dehydrogenase activities. These patients' case-reports have been analyzed. Nearly half the patients (47/100) had a malignant disease

[Renal infarct in the adult: apropos of a case].

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OBJECTIVE To report a case of renal infarction in a patient on anticoagulant therapy for aortic and tricuspid valvulopathy, with special reference to the diagnostic difficulty. METHODS The most common causes of this condition, its forms of presentation, diagnostic methods, and therapeutic approaches

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury

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Heparin is a naturally occurring, complex glycosaminoglycan that has anticoagulant activity and has been used for decades as an antithrombotic agent in management of patients at high risk for thromboses. Heparin is synthesized in mast cells as a polymer from glucuronic acid and glucosamine residues,

[Expression of PTEN, Cx43, and VEGF in hepatocellular carcinoma].

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OBJECTIVE Previous studies showed that expression of phosphatase and tensin homology deleted on chromosome ten (PTEN), gap junction protein connexin 43 (Cx43) and vascular endothelial growth factor (VEGF) may play an important role in tumor occurrence and progression. This study was designed to

[Correlation of alpha fetoprotein with the prognosis of hepatocellular carcinoma after hepatectomy in an ethnic Chinese population].

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OBJECTIVE To explore the correlation between alpha fetoprotein (AFP) and the prognosis of hepatocellular carcinoma after hepatectomy in an ethnic Chinese population. METHODS This study retrospectively analyzed the surgical outcomes of hepatocellular carcinoma (HCC) in 779 patients undergoing hepatic

Cases from the Osler Medical Service at Johns Hopkins University. Antiglomerular basement membrane disease.

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A 47-year-old Taiwanese man with no notable medical history was admitted with low-grade fevers and night sweats that had persisted for 5 to 6 weeks. An extensive investigation at another hospital could not determine the cause of the fevers, but documented acute renal failure with a blood urea

Acute toxicity of lipiodol infusion into the hepatic arteries of dogs.

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OBJECTIVE The authors studied the acute toxicity of percutaneous transcatheter hepatic artery infusion of iodized poppy oil fatty acid ester (Lipiodol, Laboratoire Guerbet, Aulnay-sous-Bois, France). METHODS Lipiodol dosages of 0, 0.25, 0.5, 1.0, and 2.0 mL/kg were infused into the hepatic arteries

A phase II study of PS-341 (Bortezomib) in advanced or metastatic urothelial cancer. A trial of the Princess Margaret Hospital and University of Chicago phase II consortia.

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BACKGROUND Based on evidence of activity in epithelial tumors in preclinical and Phase I studies, its novel mechanism of action, and its tolerability we undertook a study of bortezomib [PS-341], a reversible proteasome inhibitor, for patients with advanced or metastatic urothelial

Impaired Glycoprotein VI-Mediated Signaling and Platelet Functional Responses in CD45 Knockout Mice.

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CD45 is a receptor protein tyrosine phosphatase present on the surface of all hematopoietic cells except for erythrocytes and platelets. Proteomics studies, however, have demonstrated the presence of a CD45 c-terminal catalytic peptide in platelets. Therefore, we investigated the

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