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fawn/albumin

Krækjan er vistuð á klemmuspjaldið
GreinarKlínískar rannsóknirEinkaleyfi
12 niðurstöður

Proteinuria and impaired glomerular permselectivity in uninephrectomized fawn-hooded rats.

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Previous studies of glomerular permselectivity have indicated that both size selectivity and charge selectivity changes play a role in the pathogenesis of proteinuria. In this study, we measured Ficoll sieving coefficients, hemodynamic parameters, and urinary protein excretion rates in the FHH

Substitution of chromosome 1 ameliorates L-NAME hypertension and renal disease in the fawn-hooded hypertensive rat.

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Linkage analysis studies previously identified genetic loci associated with proteinuria and hypertension on chromosome 1 of fawn-hooded hypertensive (FHH) rats. The present studies were performed on conscious male and female rats to evaluate the influence of transfer of chromosome 1 from the Brown

Relationship between Plasma Albumin Concentration and Plasma Volume in 5 Inbred Rat Strains.

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Using the Evans Blue procedure, we previously found strain-related differences in plasma volumes in 5 inbred rat strains. Because albumin binds strongly with Evans blue, this protein is important in the Evans blue method of plasma volume determination. Therefore, we speculated that interstrain

Fluorescence dilution technique for measurement of albumin reflection coefficient in isolated glomeruli.

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This study describes a high-throughput fluorescence dilution technique to measure the albumin reflection coefficient (σAlb) of isolated glomeruli. Rats were injected with FITC-dextran 250 (75 mg/kg), and the glomeruli were isolated in a 6% BSA solution. Changes in the fluorescence of the glomerulus

The haematology and serum biochemistry of wild fallow deer (Dama dama) in New South Wales.

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Fallow deer (Dama dama) were captured in an enclosure trap in southern New South Wales. Blood samples were collected for determination of haematological and biochemical values after capture and in one group after 3 h of transportation. Results were compared between fawns and does, transported and

Serum amyloid A and plasma protein electrophoresis fractions in farmed white-tailed deer.

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Tools to measure the acute-phase response have been utilized widely in veterinary medicine. Evaluation by plasma protein electrophoresis (PPEP) has become an increasingly common assay in veterinary clinical pathology. Commercial reagents for serum amyloid A (SAA) have been validated for use in a

A 4.1-Mb congenic region of Rf-4 contributes to glomerular permeability.

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The combined transfer of two renal function quantitative trait loci (QTLs), Rf-1 (rat chromosome 1) and Rf-4 (rat chromosome 14), from the Fawn-hooded hypertensive rat onto the August Copenhagen Irish genetic background significantly increases proteinuria and demonstrates an interaction between

Blood characteristics of white-tailed deer from northeastern Kansas.

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Blood samples were collected from 118 white-tailed deer (Odocoileus virginianus) shot on the Fort Riley Military Installation in northeastern Kansas. Values for these deer for hematocrit, glucose, alkaline phosphatase, uric acid, total protein, albumin, and calcium were within the ranges reported in

Rab38 modulates proteinuria in model of hypertension-associated renal disease.

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We previously reported that the fawn-hooded hypertensive (FHH) rat is a natural Rab38 knockout, supported by a congenic animal (FHH.BN-Rab38) having less proteinuria than FHH animals. Because these congenic animals contain Brown Norway (BN) alleles for five other named genes; however, a causal role

Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats.

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This study examined the genetic basis for hypertension and renal disease phenotypes in Fawn Hooded hypertensive (FHH) rats using chromosome substitution strains (consomic rats) in which each of the 20 autosomes as well as the X and Y chromosomes were transferred from the normal Brown Norway (BN) rat

Blood pressure and the susceptibility to renal damage after unilateral nephrectomy and L-NAME-induced hypertension in rats.

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BACKGROUND Fawn-hooded hypertensive (FHH) rats carry several genes which determine the susceptibility to develop renal damage, while renal damage resistant August x Copenhagen Irish (ACI) rats do not. Kidneys from heterozygous (FHH x ACI) F(1) rats, appear to be largely, but not completely,

Temporal characterization of the development of renal injury in FHH rats and FHH.1BN congenic strains.

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The present study examined the effect of transfer of portions of chromosome 1 that includes (FHH.1(BN) AR(+) strain) or excludes (control FHH.1(BN) AR(-) strain) a 4.3-Mb region from the Brown Norway (BN) rat that restores the autoregulation (AR) of renal blood flow (RBF) on the development of
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