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Experimental coccidiosis in mule deer fawns.

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Five mule deer fawns (Odocoileus hemionus) ranging in age from 3 to 6 weeks were given sporulated Eimeria mccordocki oocysts orally. Four of the five fawns developed coccidiosis. Initial clinical signs appeared by 8 to 9 days postinoculation and included elevated body temperature and bloody

Diagnosis of Deerpox virus infection in a white-tailed deer (Odocoileus virginianus) fawn.

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A 3-month-old fawn from a group of 12 captive white-tailed deer (Odocoileus virginianus) displaying cutaneous lesions was presented to the Mississippi Veterinary Research & Diagnostic Laboratory for necropsy. Postmortem examination identified multiple discrete, round, alopecic, flat, proliferative

Auricular chondritis in fawn-hooded rats. A spontaneous disorder resembling that induced by immunization with type II collagen.

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A spontaneous apparently unique auricular chondritis in the pinna of fawn-hooded rats is described. The chondritis was bilateral, with adult onset, and resulted in a marked thickening of the auricular cartilage. Microscopically, islands of proliferative cartilage were present, and at the margins

Glomerular hemodynamic changes associated with arteriolar lesions and tubulointerstitial inflammation.

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Glomerular hemodynamic adaptations to loss of renal mass are thought to be the initiating factor of progression to renal failure; however, tubulointerstitial (TI) injury correlates better with progression than with glomerular damage. Thus, it is conceivable that tubulointerstitial alterations

Variability in ozone-induced pulmonary injury and inflammation in healthy and cardiovascular-compromised rat models.

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The molecular bases for variability in air pollutant-induced pulmonary injury due to underlying cardiovascular (CVD) and/or metabolic diseases are unknown. We hypothesized that healthy and genetic CVD-prone rat models will exhibit exacerbated response to acute ozone exposure dependent on the type

Invasive entamoebae in pronghorn (Antilocapra americana) from Wyoming.

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Trophozoites and cysts of an amoeba resembling Entamoeba bovis were recovered from soft stools of captive pronghorn fawns (Antilocapra americana). Chronic or intermittent diarrhea was observed in most individuals in two groups of hand-raised 1- to 8-mo-old pronghorns. Ileocecal lymph nodes were

Listeria monocytogenes subtypes associated with mortality among fallow deer (Dama dama).

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Different subtypes of Listeria monocytogenes were isolated from various animal and environmental samples during an episode of increased mortality on a fallow deer (Dama dama) farm. During a 4-wk period, six fallow deer died, including four does, one fawn, and one adult buck. Prior to death, one of

Meningeal worm in experimentally-infected bighorn and domestic sheep.

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In the first (July 1989) of two experiments, each of three bighorn sheep (Ovis canadensis) and three domestic sheep, respectively, was exposed to 25, 150, or 300 infective third-stage larvae (L3) of the meningeal worm, Parelaphostrongylus tenuis. Two bighorn sheep had temporary mild paresis and

Inherited myopathy of great Danes.

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A hereditary, non-inflammatory myopathy occurring in young great Danes with distinctive histological features in muscle biopsy specimens is reviewed. Onset of clinical signs is usually before one year of age and both sexes are affected. Clinical signs are characterised by exercise intolerance,

Role of genetic modifiers in an orthologous rat model of ARPKD.

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Human data and animal models of autosomal recessive polycystic kidney disease (ARPKD) suggest that genetic factors modulate the onset and severity of the disease. We report here for the first time that ARPKD susceptibility is attenuated by introgressing the mutated Pkhd1 disease allele from the

Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice.

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Some anti-inflammatory medications reduce alcohol consumption in rodent models. Inhibition of phosphodiesterases (PDE) increases cAMP and reduces inflammatory signaling. Rolipram, an inhibitor of PDE4, markedly reduced ethanol intake and preference in mice and reduced ethanol seeking and consumption

Clinical and pathological manifestations of cardiovascular disease in rat models: the influence of acute ozone exposure.

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Rodent models of cardiovascular diseases (CVD) and metabolic disorders are used for examining susceptibility variations to environmental exposures. However, cross-model organ pathologies and clinical manifestations are often not compared. We hypothesized that genetic CVD rat models will exhibit

Polymorphisms within the canine MLPH gene are associated with dilute coat color in dogs.

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BACKGROUND Pinschers and other dogs with coat color dilution show a characteristic pigmentation phenotype. The fur colors are a lighter shade, e.g. silvery grey (blue) instead of black and a sandy color (Isabella fawn) instead of red or brown. In some dogs the coat color dilution is sometimes

Demography and health of Pugs under primary veterinary care in England.

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BACKGROUND The Pug is an ancient dog breed and was the fifth most commonly registered UK pedigree breed in 2014. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory and dermatological problems. The VetCompass Programme collates de-identified

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