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fibrosis/fatigue

Krækjan er vistuð á klemmuspjaldið
Bls 1 frá 723 niðurstöður

Factors related to fatigue in patients with cirrhosis before and after liver transplantation.

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OBJECTIVE We performed a prospective study to evaluate fatigue and identify potential determinants among patients with cirrhosis. We also studied the effects of liver transplantation on fatigue in these patients. METHODS A total of 108 patients with cirrhosis being evaluated before liver

Relationship between Physical Activity and Fatigue in Adults with Cystic Fibrosis.

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Purpose: We examined the relationship between the amount of physical activity and level of fatigue in adults with cystic fibrosis (CF). Method: Participants were recruited from the Toronto Adult Cystic Fibrosis Centre at St. Michael's Hospital. Participants completed the Habitual Activity Estimation

[Fatigue, loss of appetite and anuria due to retroperitoneal fibrosis].

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Two men aged 58 and 76, respectively, presented with fatigue and loss of appetite followed by anuria. Laboratory tests showed anaemia, elevated ESR and renal failure. CT of the abdomen revealed obstruction of the ureters by retroperitoneal fibrosis. The first patient had retroperitoneal fibrosis in
BACKGROUND We have previously reported, in an uncontrolled trial, an improvement in fatigue scores in patients with primary biliary cirrhosis given oral antioxidant supplementation. We now present data from a controlled trial. METHODS Sixty-one patients with primary biliary cirrhosis-associated
Rhinitis symptoms are present in approximately 70% of subjects with fibromyalgia and chronic fatigue syndrome (FM/CFS). Because only 35% to 50% have positive allergy skin tests, nonallergic mechanisms may also play a role. To better understand the mechanisms of nonallergic rhinitis in FM/CFS, nasal

Fluoxetine for the treatment of fatigue in primary biliary cirrhosis: a randomized, double-blind controlled trial.

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Fatigue is a common symptom in primary biliary cirrhosis (PBC). In animal models of cholestasis, abnormalities in serotonin neurotransmission are observed with fatigue. The role of selective serotonin reuptake inhibitors in fatigue-related PBC, however, is unknown. A double-blind, placebo-controlled

Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis.

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OBJECTIVE Primary biliary cirrhosis (PBC) is characterized in 95% of patients by autoantibody responses directed against the mitochondrial antigen pyruvate dehydrogenase complex (PDC). Although anti-PDC inhibits PDC function in vitro, mitochondrial function in vivo in PBC has not been

[The Relationship Between Fatigue and Uncertainty in Patients With Liver Cirrhosis].

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Cirrhosis is a chronic, progressive, and currently incurable disease. Cirrhotic patients often experience uncertainty due to poor control of symptoms and disease recurrence. Although fatigue is a common symptom in patients with liver cirrhosis, this symptom is often ignored by healthcare

Neuroactive steroids and fatigue severity in patients with primary biliary cirrhosis and hepatitis C.

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Fatigue is one of the most common non-specific symptoms associated with several disease states including liver diseases. Recently, it was reported that levels of progesterone metabolites such as allopregnanolone (3alpha,5alpha-tetrahydroprogesterone; 3alpha,5alpha-THP) and isopregnanolone

Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use.

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OBJECTIVE Fatigue is the commonest symptom of the chronic liver disease primary biliary cirrhosis (PBC). PBC is increasingly being diagnosed earlier in its natural history at a stage when concerns about progression to liver failure may be less prominent than current symptoms. The importance of

A phenomenological study of fatigue in patients with primary biliary cirrhosis.

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OBJECTIVE This paper reports the findings of research on the lived experience of fatigue in patients with primary biliary cirrhosis - a type of chronic liver disease. BACKGROUND Fatigue is a universal phenomenon, commonly associated with both acute and chronic illness, but also seen in healthy

A predictive model for fatigue and its etiologic associations in primary biliary cirrhosis.

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OBJECTIVE Excessive day-time somnolence and autonomic dysfunction are biological processes prevalent in Primary Biliary Cirrhosis (PBC) that associate with fatigue. Here we explore how these biological associates inter-relate, and their cumulative impact upon typical clinical cohorts. METHODS A

Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice.

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BACKGROUND Duchenne muscular dystrophy (DMD) is a severe and progressive muscle-wasting disorder caused by mutations in the dystrophin gene that result in the absence of the membrane-stabilising protein dystrophin. Dystrophic muscle fibres are susceptible to injury and degeneration, and impaired

Bupropion for fatigue and as a tumor necrosis factor-alpha lowering agent in primary biliary cirrhosis.

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Primary biliary cirrhosis (PBC) is a chronic cholestatic disease which can often be severe, progressive and necessitate liver transplantation. The cause of PBC is not known, and treatments other than liver transplantation are often not effective. Among the more common and troublesome symptoms of PBC
BACKGROUND Fatigue is a major clinical problem in many patients with primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). An effective treatment has not been defined. Recently, a large proportion of patients with these diseases was found to have symptoms of depression. Because
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