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Characterization of submicron MCT o/w emulsions using sedimentation field-flow fractionation (FFF) with power field programming.

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Sedimentation field-flow fractionation (SdFFF) operated with power-based field programming, was shown to be effective in the characterization of submicron investigational pharmaceutical emulsions. Field programming, in which the decrease of field strength with time gradually decreases the retention

Enzyme field effect transistor (ENFET) for estimation of triglycerides using magnetic nanoparticles.

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Ion-selective field effect transistor (ISFET) is a robust platform to develop biosensors. A variety of methods are used including covalent attachment or polymer entrapment, to associate enzymes or antibodies to the gate surface of a FET. We have employed a novel method of retaining the enzyme

More clinical lessons from the FIELD study.

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BACKGROUND The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study investigated the effect of fenofibrate treatment in 9,795 patients with type 2 diabetes. CONCLUSIONS Reduction in major coronary events (the primary endpoint) and total cardiovascular disease (CVD) events (the

Measurements of size distribution and density of a pharmaceutical fat emulsion, using field-programmed sedimentation field-flow fractionation (SdFFF).

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OBJECTIVE The main goal was to establish that sedimentation field-flow fractionation (SdFFF), operated with power based field programming, is effective in the characterization of a commercial emulsion, Medialipide. This emulsion is used clinically for total parenteral nutrition and it is consisted

Type A behavior, field dependence, and serum lipids.

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Given evidence that individual differences on the cognitive style dimension of field dependence/independence are significantly related to sympathetically mediated cardiovascular functioning and lipid metabolism, a correlational study was designed to examine associations between Type A behavior,

Effect of pulsed magnetic fields on cholesterol and tryglyceride levels in rats study of field intensity and length of exposure.

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In a previous work a decrease in cholesterol and triglyceride plasma levels was observed in rats 24 hours after their exposure to a 12 Hz 6 mT pulsed magnetic field (PMF). This time, a study of intensity effects of a 12 Hz PMF for a sixty-minute exposure and of length of exposure for a 12 Hz 6 mT

Statins improve visual field alterations related to hypercholesterolemia.

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OBJECTIVE To determine whether lipid-lowering treatment with diet or statins would provide beneficial effects on visual field alterations associated with hypercholesterolemia. METHODS 180 subjects with hypercholesterolemia were randomly assigned to a low fat diet (diet group) or to a low fat diet

Postprandial lipemia: reliability in an epidemiologic field study.

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Ten subjects from the Forsyth County, North Carolina, and Washington County, Maryland, field centers in the Atherosclerosis Risk in Communities Study had two fat tolerance tests within a 10-day period from September 1988 to February 1989 to determine the reproducibility of markers for postprandial

Effect of pulsed magnetic fields on triglyceride and cholesterol levels in plasma of rats.

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BACKGROUND Liver is a crucial organ in metabolism. For instance liver is the main source of circulating lipoproteins. METHODS In this paper cholesterol and triglyceride plasma levels were measured in male rats previously exposed to pulsed magnetic fields (PMF) used in therapy. Rats underwent a

Laboratory and field evaluation of three desktop instruments for assay of cholesterol and triglyceride.

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We evaluated three desktop instruments suitable for decentralizing the assays of blood cholesterol and triglycerides to satellite and physician's office testing. The instruments, Ektachem DT 60 (E), Reflotron (R), and Seralyzer (S), were used according to their manufacturers' instructions to assay

Age Dependency of Myocardial Triglyceride Content: A 3T High-Field 1H-MR Spectroscopy Study.

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OBJECTIVE The role of myocardial triglyceride (mTG) content in the aging human heart is not entirely understood. The aim of this study was to measure concentrations of mTG content from healthy volunteers and to determine the association between age, mTG content and systolic heart function.

Studies of exposure of rabbits to electromagnetic pulsed fields.

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Dutch rabbits were acutely exposed to electromagnetic pulsed (EMP) fields (pulse duration 0.4 mus, field strengths of 1--2 kV/cm and pulse repetition rates in the range of 10 to 38 Hz) for periods of up to two hours. The dependent variables investigated were pentobarbital-induced sleeping time and

Fibrates after the FIELD study: Some answers, more questions.

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Fibrates have a long history in cardiovascular disease. These drugs raise high-density lipoprotein (HDL)-cholesterol, reduce triglycerides and improve small dense low-density lipoprotein (LDL) so would be expected to have large effects in type 2 diabetes, where this is the typical lipid profile. The

Hypertension and macrovascular disease--the killing fields of NIDDM.

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Diabetes mellitus and particularly non-insulin-dependent diabetes mellitus (NIDDM) increases the risk for all manifestations of: (a) atherosclerotic vascular disease; (b) coronary heart disease (CHD); (c) cerebrovascular disease; and (d) peripheral vascular disease. NIDDM is known to be associated

Role for fibrate therapy in diabetes: evidence before FIELD.

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OBJECTIVE Diabetic dyslipidaemia, among the main factors contributing to vascular risk in type 2 diabetes, is characterized by hypertriglyceridaemia, low HDL-cholesterol and increased prevalence of small dense LDL particles. Because fibrates have positive effects on triglycerides, HDL-cholesterol

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