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hydrocarbon/seizures

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GreinarKlínískar rannsóknirEinkaleyfi
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Nonallelism for the audiogenic seizure prone (Asp1) and the aryl hydrocarbon receptor (Ahr) loci in mice.

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Previous studies showed an association between the Ahr locus on Chr 12 and a major gene, Asp1, that influences susceptibility to audiogenic seizures (AGS) in mice. Although the association was thought to involve close linkage, a pleiotropic effect of the Ahr locus on AGS susceptibility was not

Genetic linkage between the AH locus and a major gene that inhibits susceptibility to audiogenic seizures in mice.

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Mice of the DBA/2 (D2) strain are highly susceptible to sound-induced seizures at 21 days of age; whereas, mice of the C57BL/6 (B6) strain are resistant to these seizures. Although the difference in susceptibility to audiogenic seizures (ASs) between these two strains is inherited as a

Seizures after eating a snack food contaminated with the pesticide endrin. The tale of the toxic taquitos.

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In September 1988 we investigated reports of seizures in persons who had eaten taquitos, a commercially prepared snack food. We identified and interviewed 5 persons with new-onset seizures within 12 hours of eating taquitos, all purchased during a 1-week period from a single store. Leftover taquitos

Thiophene, a sulfur-containing heterocyclic hydrocarbon, causes widespread neuronal degeneration in rats.

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Thiophene is a sulfur-containing heterocyclic hydrocarbon that has been detected in a number of environmental sources as various derivatives. Previous studies with rats have shown that thiophene induces selective degeneration of granule cells in the cerebellum, as observed with methyl mercury. To
The behavioral, electrographic and histopathological changes induced by the heterocyclic hydrocarbon thiophene were investigated in rats following intramuscular injection of 0.3 mL thiophene for 5 days. Generalized convulsions were noted in 29 out of 34 animals (85%) between 1 and 28 h after the

Benefits of extracorporeal membrane oxygenation for hydrocarbon pneumonitis.

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OBJECTIVE To review the therapeutic benefits of extracorporeal membrane oxygenation for the management of hydrocarbon pneumonitis. METHODS A search of the medical literature was conducted through Medline and the bibliographies of relevant articles and a search of patient databases maintained by the

Chlorinated hydrocarbon pesticides and amygdaloid kindling.

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Previous studies by our laboratory have shown that exposures to either lindane or dieldrin enhanced the rate of acquisition of the fully kindled amygdaloid seizure in the rat. To examine whether this enhancement generalizes to all groups of chlorinated hydrocarbon pesticides, the effect of

Respiratory complications following hydrocarbon aspiration in children.

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Accidental hydrocarbon ingestion may lead to aspiration and chemical pneumonitis in children. In this review article, the clinical course of hydrocarbon pneumonitis, chest radiographic abnormalities, complications, and treatment interventions are summarized. Most children remain asymptomatic and

Seizure thresholds in kindled animals are reduced by the pesticides lindane and endosulfan.

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Lindane and endosulfan are chlorinated hydrocarbon pesticides that bind to the gamma-aminobutyric-acidA (GABAA) receptor ionophore complex. We have previously demonstrated development of a persistent predisposition to the seizure-inducing properties of these pesticides following repeated

Intravascular hemolysis associated with hydrocarbon poisoning.

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Hydrocarbon ingestion may result in serious complications such as adult respiratory distress syndrome, encephalopathy, and seizures. Hematologic disorders have appeared to be rare complications of hydrocarbon toxicity. After encountering a case complicated by severe intravascular hemolysis, we
BACKGROUND Methyl bromide is a halogenated aliphatic hydrocarbon that exists as a colorless gas or a volatile liquid. Methyl bromide historically had been used in fire extinguishers but is more commonly used as a gas fumigant for soil-borne diseases and pests. Methyl bromide is being phased out due

Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling.

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Hydrocarbon stapling is an effective strategy to stabilize the helical conformation of bioactive peptides. Here we describe application of stapling to anticonvulsant neuropeptides, galanin (GAL) and neuropeptide Y (NPY), that are implicated in modulating seizures in the brain. Dicarba bridges were

The effects of neurotoxicants on kindling and kindled seizures.

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The application of a constant-amplitude electrical stimulation to many parts of the brain leads to the expression of progressively more severe epileptiform responses. The process of acquisition is termed kindling, and the acquired response is termed the kindled seizure. This state has been used in a

Hydrocarbon poisoning in children: a 5-year retrospective study.

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OBJECTIVE To investigate the demographics, incidence, and symptoms and signs of hydrocarbon poisoning in admitted children from the Negev Desert area of Israel. METHODS The medical records of all children admitted for hydrocarbon poisoning from 1995 to 1999 were reviewed retrospectively. RESULTS Of
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