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trans resveratrol/seizures

Krækjan er vistuð á klemmuspjaldið
GreinarKlínískar rannsóknirEinkaleyfi
5 niðurstöður

Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats.

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Overexcitation of excitatory amino acid is an important mechanism in seizure genesis wherein free radicals have recently been suggested to play a critical role. Thus, intervention by antioxidants can be a potential beneficial approach in the treatment of epilepsy. The present study was undertaken to

Protective effect of resveratrol against pentylenetetrazole-induced seizures and its modulation by an adenosinergic system.

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The effect of trans-resveratrol (resveratrol), a polyphenolic compound with potent antioxidant activity, was investigated against pentylenetetrazole (PTZ) induced seizures in rats. Resveratrol (20, 40, and 80 mg/kg i.p.) administered 20 min prior to convulsive challenge with PTZ (60 mg/kg i.p.) dose

Protective effect of resveratrol against intracortical FeCl3-induced model of posttraumatic seizures in rats.

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The present study was carried out to investigate the effect of trans-resveratrol, a potent antioxidant, against FeCl3-induced posttraumatic seizures. Male Wistar rats weighing 200-250 g were implanted with epidural electrodes and allowed to recover After the recording of baseline EEG. FeCl3 (5

Post traumatic epilepsy: a review of scientific evidence.

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Post traumatic epilepsy is the development of recurrent seizures following head trauma and has a high clinical relevance. Several risk factors including some genetic factors increase the susceptibility of post traumatic epilepsy. The precise mechanisms of epileptogenesis in post-traumatic epilepsy

Lack of resveratrol neuroprotection in developing rats treated with kainic acid.

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In adult rats, trans-resveratrol attenuates kainic acid (KA)-induced convulsions and the associated hippocampal neurotoxicity. Increased neuronal survival was correlated with reduced lipid peroxidation. Since free radical generation after KA is age dependent and does not correlate with the onset of
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