venous insufficiency/nikótín

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Lower limb venous insufficiency and tobacco smoking: a case-control study.

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At the present time, no study has yet clearly established whether tobacco smoking is a risk factor of lower limb venous insufficiency. This case-control study was initiated in France to determine the possible etiologic relation between tobacco smoking and lower limb venous insufficiency. A total of

Epidemiology of chronic venous insufficiency of the lower limbs in the primary care setting.

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OBJECTIVE The objective of the study was to describe the general characteristics, risk factors and clinical symptoms of patients seeking medical care at the primary care setting because of chronic venous insufficiency. METHODS A total of 606 general practitioners throughout Spain participated in

Factors associated with saphenous vein recanalization after endothermal ablation.

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BACKGROUND Endovenous thermal ablation has emerged as an alternative therapy for the treatment of chronic superficial venous insufficiency (CVI) of the lower extremities. Recanalization, or anatomic failure, of a vein after endovenous radiofrequency ablation (RFA) has been described, albeit an

Single copy of variant CYP2A6 alleles does not confer susceptibility to liver dysfunction in patients treated with coumarin.

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OBJECTIVE Coumarin, used in the treatment of chronic venous diseases, is mainly metabolized to non-toxic 7-hydroxy-coumarin by CYP2A6. At least, 3 variant alleles, CYP2A6*2, CYP2A6*3 and CYP2A6*4A, have been shown to encode catalytically defective proteins. Sporadic elevation of liver enzymes has

Use of expanded reverse sural artery flap in lower extremity reconstruction.

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Coverage of defects of the distal third portion of the leg and foot remains a challenge for surgeons. The difficulty results from the limited mobility and availability of the overlying skin, the weight-bearing requirements, and the relatively poor circulation of the skin. From January 2008 to

Radiofrequency ablation with concomitant stab phlebectomy increases risk of endovenous heat-induced thrombosis.

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Endovenous heat-induced thrombosis (EHIT) is a well-documented phenomenon that follows endovenous ablation, but the treatment, surveillance, and risk factors for EHIT have yet to be comprehensively elucidated. We sought to identify characteristics that may put patients at higher risk for development

A retrospective analysis of venous ulcer healing in current and former users of injected drugs.

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OBJECTIVE This study examined persons with a history of heroin injection who sought wound care for lower extremity venous ulcers and explored factors that affected their wound healing. METHODS Descriptive, retrospective data were obtained by review of the medical records of an outpatient, urban

Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction.

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BACKGROUND Endothelial dysfunction contributes significantly to the development of vascular diseases. However, a therapy able to reduce this derangement still needs to be identified. We evaluated the effects of pharmacological inhibition of Rac1, a small GTPase protein promoting oxidative stress, in

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Herbal & Natural Medicine

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