[A case of hepatocellular carcinoma in an elderly patient that improved upon combination therapy of Lentinan and Tegafur].

The case was an 83-year-old man whose chief complaint was right-hypochondralgia and high fever. His laboratory findings at the first visit revealed liver dysfunction and an elevation of AFP level. Abdominal ultra-sonography revealed a giant tumor in his liver. Because of his advanced age and the large size of his tumor, he was given 2 mg Lentinan a week and 750 mg Tegafur every day. After 3 months his serum AFP level decreased to normal range, and on computed tomography his tumor disappeared completely 6 months after the beginning of this therapy. We recommend the combination therapy of Lentinan and Tegafur for patients with a high risk for usual therapies like this case for their quality of life.