Nucleic Acids Research 1997-Mar
Colorimetric detection of immobilised PCR products generated on a solid support.
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By extending functional primers attached to a solid phase and incorporating a digoxigenin label, it is possible to visualise PCR products as discrete spots on specific regions of a solid support after colorimetric detection. The technique has been used for the detection of the point mutation associated with porcine malignant hyperthermia.