The Japanese journal of experimental medicine 1985-Aug
Effect of Bordetella pertussis vaccine on bleeding time, whole blood coagulation time and platelet aggregation in animals.
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Bordetella pertussis vaccine, a hypoglycemic agent significantly prolonged the bleeding time and whole blood coaguistion time in rabbits and dogs when administered intraperitonially. The vaccine also affects platelet aggregation in rats 4 days after its intraperitonial administration. The effect on platelet aggregation is thought to be due to its beta adrenargic receptor blocking action which may also contribute to the hypoglycemia.
