[Effects of saccharose diet and drinking water with different mineral composition on calcium-phosphorus metabolism in the teeth and bones of rats].
Parole chiave
Astratto
Metabolism of 32P and 45Ca in the teeth and bones was studied in 140 Wistar rats that received a high-saccharose diet and varying amounts of Ca, Mg and F in drinking water. The water hardness and F content influence 45Ca and 32P metabolism in the teeth and bones and caries development. 45Ca and 32P inclusion into mineralized tissues was decreased in rats fed with the high-saccharose diet as compared to the control animals which received a usual ration. Excessive consumption of Ca and Mg with drinking water was conductive to mineralization. The level of 45Ca and 32P inclusion in these groups was closer to the control. Fluorination of drinking water of varying hardness decreased caries development and increased 32P and 45Ca inclusion into mineralized tissues.