[Pathogenesis of experimental intracerebral hemorrhages in the presence of hypertension in light of microcirculatory studies].

The pathogenesis of early stages of cerebral hemorrhages was studied in albino rats with hypertension induced by an acoustic irritant in conjunction with hypoxia. Such hemorrhages developed during fibrinolysis activation and autoregulation failure of brain circulation marked by dilatation of arterioles and venules as well as by increased number of the functioning capillaries in the presence of overexcitation of the sympathoadrenal system. Multiple hemorrhages in the arterioles, venules and capillaries seen in the model tested are discussed in the light of these changes in microcirculation.