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Medicine 2018-Jun

Rhabdomyolysis following status epilepticus with hyperuricemia: A case report and literature review.

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Il collegamento viene salvato negli appunti
Lingxing Wang
Shanyan Hong
Honghong Huang
Meili Yang

Parole chiave

Astratto

BACKGROUND

Rhabdomyolysis owing to status epilepticus (SE) can be life-threating, with acute kidney injury (AKI) the most serious complication; therefore, early recognition of the risk factors is important. Hyperuricemia after epileptic seizures has been reported, and severe hyperuricemia can lead to acute renal function damage.

UNASSIGNED

We present the case of a 21-year-old man hospitalized for SE, who had especially high level of blood uric acid (UA) at initial presentation.

METHODS

The patient was diagnosed with rhabdomyolysis due to SE.

METHODS

The patient was treated with hydration and bicarbonate therapy. But he developed acute kidney failure (AKF) and hemodialysis was performed.

RESULTS

After hemodialysis, his symptoms disappeared and laboratory data returned to normal.

CONCLUSIONS

Hyperuricemia after SE might indicate severe muscle damage or reduced clearance of metabolites, and could be a risk factor for kidney dysfunction, especially with rhabdomyolysis. To our knowledge, this is the first report of rhabdomyolysis following SE with hyperuricemia.

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