[Two-year trial of the fluoride-containing varnishes Duraphat and Carex].
Parole chiave
Astratto
Previous studies have shown that topical application of the fluoride varnish Duraphat reduces caries incidence. The aim of the present study was to compare the caries inhibiting effect of a new fluoride varnish (Carex) containing 1.80% fluoride (F) with that of Duraphat (2.26%F). Informed consent was obtained from the guardians of 495 10-12-years-olds in Voss Dental Health District (low F area). The children were randomly allocated to two groups. One group of subjects received six-monthly applications of Duraphat (n = 206), the other Carex (n = 189). Ethical considerations precluded the use of a placebo varnish. All participants received dental examinations including one pair of posterior bitewing radiographs and necessary dental care annually. One trained examiner interpreted bitewing radiographs blindly. Total mean 2-year net DFS increment for 24 posterior approximal surfaces was 1.79 (s = 3.12) in the Duraphat group and 1.53 (s = 2.92) in the Carex group, a difference which was non-significant (P greater than 0.40). Thus it seems that Carex and Duraphat have approximately the same caries-preventive effect on posterior approximal surfaces.