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activated protein c resistance/hypoxia
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5 risultati
Changes of coagulation parameters during high altitude expedition.
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BACKGROUND
Data on changes of haemostatic parameters at altitudes above 5000 m are very limited. So far it is unknown, whether altered coagulation could contribute to the development of acute mountain sickness.
METHODS
Thirty four healthy mountaineers were randomised to two acclimatisation protocols
[Coronary thrombosis on patient with the factor V Leiden mutation].
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We report a documented observation of coronary thrombosis occurring in a 25-year-old patient with no risk factor, presenting a hereditary thrombophilia (facteur V Leiden) diagnosed a few months earlier in a context of venous thrombosis. This patient had a spread out anterior myocardial infarction
Low arterial saturation is associated with increased sensitivity to activated protein C in children with congenital heart disease.
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OBJECTIVE
Children with congenital heart disease experience both hemorrhagic and thrombotic complications. In this report the authors test the hypothesis that hypoxemia is associated with altered sensitivity to activated protein C (aPC) in pediatric patients with congenital heart lesions.
METHODS
A
Air travel-associated venous thromboembolism.
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Long-distance air travel is increasing and cases of venous thromboembolism (VTE) following air travel have attracted both considerable public attention and legal claims against airlines. VTE is a common disorder worldwide with a notably high incidence in older individuals. Many biochemical factors
[Pathophysiology and clinical manifestations in pre-eclampsia].
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BACKGROUND
Preeclampsia is a progressive, multisystem disorder characterised by hypertension and proteinuria. A body of evidence suggest a genetic basis; it is generally accepted that the underlying pathological processes are in the placenta.
METHODS
This article is a review of the pathophysiology
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