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agammaglobulinemia/carbohydrate
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Chronic diarrhea associated with hypogammaglobulinemia and enteropathy in infants and children.
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In order to define the gastrointestinal manifestations and small intestinal structure and function in a group of infants with chronic nonspecific diarrhea and hypogammaglobulinemia, we retrospectively identified 55 such patients from a population of 518 children evaluated for chronic diarrhea over a
Lymphoid cell lines from patients with "non-secretory" agammaglobulinemia produce glycosylated heavy chains which are reduced in molecular weight.
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B lymphocytes from patients with "non-secretory" agammaglobulinemia synthesize but do not secrete Ig. A previous study attributed this secretion failure to a failure of the cells to glycosylate Ig. We examined four B cell lines from three patients with "non-secretory" agammaglobulinemia as a model
Survival of antigen-specific antibody following administration of intravenous immunoglobulin in patients with primary immunodeficiency diseases.
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To measure the survival of IgG, IgG subclasses and antigen-specific antibody in immune-deficient patients, we infused 4 patients with X-linked agammaglobulinemia (XLA) and 6 patients with common variable immune deficiency (CVID) with modified immunoglobulin at a dose of 400 mg/kg per month until
Antibody deficiency syndromes and novel immunodeficiencies.
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Antibody deficiency syndromes can be quantitative or qualitative. The major categories of antibody deficiency syndrome are: (1) X-linked agammaglobulinemia, involving the maturation arrest in the development of the B cells; (2) transient agammaglobulinemia, which affects both sexes is often
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