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catechol/infiammazione
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Catechol carboxylic acids
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BRIEF DESCRIPTION OF THE INVENTION
The invention relates to catechol carboxylic acid derivatives of the formula ##STR7## wherein R.sub.1 is ##STR8## hydrogen, acetyl, hydroxy or alkanoyloxy, R.sub.2 is ##STR9## hydroxy, hydrogen or alkanoyloxy, wherein R is hydrogen, lower alkyl or
Catechol carboxylic acids
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Entra registrati
BRIEF DESCRIPTION OF THE INVENTION
The invention relates to catechol carboxylic acid derivatives of the formula ##STR7## wherein R.sub.1 is ##STR8## hydrogen, acetyl, hydroxy or alkanoyloxy, R.sub.2 is ##STR9## hydroxy, hydrogen or alkanoyloxy, wherein R is hydrogen, lower alkyl or
Catechol diethers as selective PDE.sup.IV inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to a series of 4-substituted catechol diether compounds which are selective inhibitors of phosphodiesterase (PDE) type IV and as such are useful in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive airways disease, psoriasis,
Therapeutically active compounds based on indazole bioisostere replacement of catechol in PDE4 inhibitors
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FIELD OF THE INVENTION
The present invention is in the field of compositions of matter, and pharmaceutical compositions and methods of treatment utilizing one or more of said compositions of matter as the active ingredient and the active agent with respect thereto, wherein said composition of matter
Catechol derivatives and pharmaceutical compositions thereof for inhibiting anaphylaxis (SRS-A)
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FIELD OF THE INVENTION
This invention relates to novel catechol derivatives useful for medicaments and intermediates thereof.
BACKGROUND OF THE INVENTION
It is generally considered that in allergic asthma and other atopic diseases of man or anaphylactic shock in animals, several chemical mediators
Catechol diether compounds as inhibitors of TNF release
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BACKGROUND OF THE INVENTION
This invention relates to a method of inhibiting production of TNF (tumor necrosis factor) in a mammal in need thereof which method comprises administering to said mammal an effective amount of a compound of the formula (I) (shown below) or a pharmaceutically acceptable
4-(or 5-) substituted catechol derivatives
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FIELD OF THE INVENTION
The invention relates to 4-substituted or 5-substituted catechol derivatives that are useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical compositions comprising these compounds, and to methods for the treatment of
Catechol diethers derivatives useful as pharmaceutical agents
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BACKGROUND OF THE INVENTION
This invention relates to catechol diethers containing a long lipophilic sidechain which are selective inhibitors of phosphodiesterase (PDE) type IV or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of asthma, arthritis, bronchitis,
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