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Pagina 1 a partire dal 27 risultati
Controlling the growth of certain tumor tissue with chalcone derivatives
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FIELD OF THE INVENTION
This invention relates to the use of certain antimitotic chalcone derivatives which are useful in controling the growth of tumor tissue.
BACKGROUND OF THE INVENTION
Cell division in eukaryotic cells is divided into two sequential phases, mitosis followed by cytokinesis. At the
Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds
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This application is a national stage application under 35 U.S.C. .sctn.371 from PCT Application No. PCT/KR2007/006337, filed Dec. 7, 2007, which claims the priority benefit of Korean Application No. 10-2006-0124146, filed Dec. 7, 2006.
TECHNICAL FIELD
The present invention relates to a method for
Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds
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TECHNICAL FIELD
The present invention relates to a method for screening an anticancer compound, and more particularly, to a method for screening a compound inhibiting TM4SF5-mediated tumor formation, development and metastasis. Also, the present invention is concerned with a chalcone compound
Treatment of bladder and urinary tract cancers
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FIELD OF THE INVENTION
The present invention relates generally to biology and medicine, and more particularly to compositions and methods for treating bladder and urinary tract cancers.
BACKGROUND OF THE INVENTION
New therapies and improved diagnoses of bladder cancer have significantly lowered the
Chalcone coumarins
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FIELD OF THE INVENTION
The invention relates to a novel class of compounds which have a structures related to naturally and synthetically occurring chalcones, as well as to methods for preparation of such compounds and to pharmaceutical uses thereof.
TECHNICAL FIELD
The compound
Chalcones
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FIELD OF THE INVENTION
The present invention relates to a novel class of compounds which have structures related to certain naturally occurring and synthetic chalcones, as well as to methods for the preparation of such compounds and to pharmaceutical uses thereof.
TECHNICAL FIELD
The compound
Chalcone retinoids and methods of use of same
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CROSS-REFERENCE TO RELATED APPLICATION
This application claims the benefit of U.S. Provisional Application No. 60/000,057, filed Jun. 8, 1995.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to novel retinoids, as coumarin retinoids and/or purine retinoids, and
Heteroaromatic chalcone derivatives and their medical use
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This application is a national phase application under 35 U.S.C. .sctn. 371 of International Application No. PCT/EP2015/069758, filed Aug. 28, 2015, which claims benefit of European Application No. 14182679.2, filed Aug. 28, 2014, the entire contents of each of which are hereby incorporated by
Modified chalcone compounds as antimitotic agents
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FIELD OF THE INVENTION
The present invention relates to antimitotic agents of the formula CHAL-LIN-COV, having a chalcone or chalcone derivative portion (CHAL) and a covalent bonding portion (COV) that is optionally bonded to CHAL through a linker portion (LIN). The covalent bonding portion may be
Modified chalcone compounds as antimitotic agents
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FIELD OF THE INVENTION
The present invention relates to antimitotic agents of the formula CHAL-LIN--COV, having a chalcone or chalcone derivative portion (CHAL) and a covalent bonding portion (COV) that is optionally bonded to CHAL through a linker portion (LIN). The covalent bonding portion may be
Substituted chalcones as therapeutic compounds
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TECHNICAL FIELD
This invention pertains to substituted chalcones, specifically substituted 1-(4-methoxyphenyl)-3-(3,5-dimethoxyphenyl)prop-1-en-3-ones, which have therapeutic application, for example, as potent antiproliferative agents and antiinflammatory agents. The present invention also pertains
Method of treating multiple sclerosis with chalcone derivatives
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FIELD OF THE INVENTION
This invention relates to certain chalcone derivatives which inhibit the destruction of the myelin sheath covering the axons of the central nervous system and are thus useful in the treatment of multiple sclerosis.
BACKGROUND OF THE INVENTION
Cell division in eukaryotic cells
Coumarin-chalcones as anticancer agents
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a National Phase of and claims the benefit of PCT/IN2011/000515, with an international filing date of Aug. 5, 2011, which in turn claims priority to Indian Application No. 1843/DEL/2010, filed Aug. 5, 2010, the entire disclosures of
Boronic chalcone derivatives and uses thereof
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel boronic chalcone compounds and uses thereof. The compounds of this invention are particularly useful for the treatment of tumors and cancers.
2. Description of the State of the Art
Throughout this application,
O-phenyl chalcone compounds and uses thereof
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FIELD OF THE INVENTION
The present invention is in the field of medicinal chemistry, and particularly relates to o-phenyl chalcone compounds and preparation methods and uses thereof.
BACKGROUND OF THE INVENTION
Malignant tumors are diseases severely threatening human health. Chemotherapy continues
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