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chemotherapy/ictus
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Pagina 1 a partire dal 36 risultati
Chinese medicine composition for treating leukemia bone marrow transplant failure complicated by brain stem stroke after chemotherapy
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present disclosure relates to a composition for treating leukemia bone marrow transplant failure complicated by cerebral vascular disease after chemotherapy, particularly a composition for treating leukemia bone marrow transplant failure
Substituted piperidines as soluble epdxide hydrolase inhibitors
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BACKGROUND OF THE INVENTION
Pain is generally divided into nociceptive and neuropathic pain. Nociceptive pain stems from neural pathways in response to tissue damaging or potentially tissue damaging signals, and includes inflammatory pain. Neuropathic pain tends to relate to dysfunctions within the
Neurosteroid compounds
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This is a National Phase Application in the United States of International Patent Application No. PCT/GB2008/002067, filed Jun. 17, 2008, which claims priority to Great Britain Patent Application No. 0711948.0, filed Jun. 20, 2007.
FIELD OF THE INVENTION
This invention pertains to neurosteroid
Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use
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TECHNICAL FIELD OF INVENTION
This invention relates to physiologically acceptable aqueous emulsions of perfluorocarbon ether hydrides having 8 to 12 carbon atoms. The novel emulsions have various medical applications. They are especially useful medically as contrast media for various biological
Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods of use
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TECHNICAL FIELD OF INVENTION
This invention relates to physiologically acceptable aqueous emulsions of perfluorocarbon ether hydrides having 8 to 12 carbon atoms. The novel emulsions have various medical applications. They are especially useful medically as contrast media for various biological
Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
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TECHNICAL FIELD OF INVENTION
This invention relates to compositions comprising highly fluorinated, chloro-substituted, non-cyclic organic compounds having 7 to 9 carbon atoms and to processes of making and using them. More particularly, this invention relates to emulsions comprising those highly
Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of making and using them
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TECHNICAL FIELD OF INVENTION
This invention relates to compositions comprising highly fluorinated, chloro-substituted, non-cyclic organic compounds having 7 to 9 carbon atoms and to processes of making and using them. More particularly, this invention relates to emulsions comprising those highly
Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease
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Disclosed herein are new substituted bicyclo[1.1.1]pentane compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of the kinase activity of dual leucine zipper in a human or animal subject are also provided for the treatment of
Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease
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Disclosed herein are new substituted bicyclo[1.1.1]pentane compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of the kinase activity of dual leucine zipper in a human or animal subject are also provided for the treatment of
Benzimidazolone derivatives as CB2 receptor ligands
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone derivatives. These compounds have selective cannabinoid(CB)2 receptor binding activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the
Sulfonyl benzimidazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to sulfonyl benzimidazole derivatives. These compounds have selective cannabinoid (CB)2 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
Piperazino[1,2-a]indol-1-ones and [1,4]diazepino[1,2-a]indol-1-one
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BACKGROUND OF THE INVENTION
Neurogenesis occurs in the developing and adult brain. Conceptually, this process of neurogenesis can be divided into four steps: (i) proliferation of NSCs; (ii) neuronal fate determination of NSC; (iii) survival and maturation of new neurons; and (iv) functional
1,7-naphthyridine derivatives
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation of International Application No. PCT/EP2014/066123 having an international filing date of Jul. 28, 2014 and which claims benefit under 35 U.S.C. .sctn.119 to European Patent Application No. 13178373.0 filed Jul. 29, 2013. The
Benzisoxazoles
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BACKGROUND OF THE INVENTION
Now it has been shown that the present compounds stimulate neurogenesis from neural stem cells (NSCs). Neurogenesis occurs in the developing and adult brain. Conceptually, this process of neurogenesis can be divided into four steps: (i) proliferation of NSCs; (ii)
Imidazopyridine derivatives
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The present invention relates to compounds of general formula
##STR00002## wherein Ar is phenyl or pyridinyl; X.sup.1 is N or CH, X.sup.2 is N or CH, with the proviso that only one of X.sup.1 or X.sup.2 is N and the other is CH; R.sup.1 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkyl
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